Reply to the Commentary on the article “Sepsis in children: federal guidelines (draft)” I.А. Savin

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Abstract

The authors of the Clinical Guidelines are grateful to Professor I.A. Savin for his comments and provide answers to the comments made regarding the appointment of antibacterial drugs and immunoglobulins for sepsis in children.

About the authors

Andrey U. Lekmanov

Pirogov Russian Research Medical University

Author for correspondence.
Email: aulek@rambler.ru
ORCID iD: 0000-0003-0798-1625
SPIN-code: 3630-5061

Dr. Sci. (Med.), Professor

Russian Federation, 1 Ostrovityanova str., 117997, Moscow

Dmitry А. Popov

Bakulev National Medical Research Center for Cardiovascular Surgery

Email: da_popov@inbox.ru
ORCID iD: 0000-0003-1473-1982
SPIN-code: 6694-6714

Dr. Sci. (Med.)

Russian Federation, 1 Ostrovityanova str., 117997, Moscow

References

  1. Weiss SL, Peters MJ, Alhazzani W, et al. Surviving Sepsis Campaign International Guidelines for the Management Sepsis and Septic Shock and Sepsis-associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020;21(2):e52–e106. doi: 10.1097/PCC.0000000000002198
  2. El-Nawawy A, El-Kinany H, Hamdy El-Sayed M, Boshra N. Intravenous polyclonal immunoglobulin administration to sepsis syndrome patients: a prospective study in a pediatric intensive care unit. J Trop Pediatr. 2005;51(5):271-278. doi: 10.1093/tropej/fmi011
  3. Ohlsson A, Lacy JB. Intravenous immunoglobulin for suspected or proven infection in neonates. Cochrane Database Syst Rev. 2013;(7):CD001239. doi: 10.1002/14651858.CD001239.pub4. Corrected and republished from: Cochrane Database Syst Rev. 2015;(3):CD001239. doi: 10.1002/14651858.CD001239.pub5
  4. INIS Collaborative Group; Brocklehurst P, Farrell B, King A, et al. Treatment of neonatal sepsis with intravenous immune globulin. N Engl J Med. 2011;365(13):1201–1211. doi: 10.1056/NEJMoa1100441
  5. Beloborodova NV, Popov DA, Shatalov KV, et al. Zamestitel’naja immunoterapija pod kontrolem testa na prokal’citonin – novyj podhod k preduprezhdeniju manifestacii infekcii v posleoperacionnom periode u detej so slozhnymi vrozhdennymi porokami serdca. Heart and Vessels Diseases in Children. 2005;3:62–68. (In Russ.)
  6. Abdullayev E, Kilic O, Bozan G, et al. Clinical, laboratory features and prognosis of children receiving IgM-enriched immunoglobulin (3 days vs. 5 days) as adjuvant treatment for serious infectious disease in pediatric intensive care unit: a retrospective single-center experience (PIGMENT study). Human Vaccines & Immunotherapeutics. 2020;16(8):1997–2002. doi: 10.1080/21645515.2019.1711298
  7. Martinez J-I, Sánchez H-F, Velandia J-A, et al. Treatment with IgM-enriched immunoglobulin in sepsis: a matched case-control analysis. J Crit Care. 2021;64:120–124. doi: 10.1016/j.jcrc.2021.03.015

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