Effectiveness of endoscopic treatment of duplex system ureteroceles in children
- Authors: Dubrov V.I.1, Strotsky A.V.2, Shkutov A.O.1
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Affiliations:
- 2nd Сity Children’s Clinical Hospital
- Belarusian State Medical University
- Issue: Vol 10, No 1 (2020)
- Pages: 25-34
- Section: Original Study Articles
- URL: https://journals.rcsi.science/2219-4061/article/view/123448
- DOI: https://doi.org/10.17816/psaic648
- ID: 123448
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Abstract
Objective. The aim of this study is to evaluate the efficiency of transurethral incision of ureteroceles and incidence of vesicoureteral reflux in pediatric patients with duplex system ureterocele.
Materials and methods. This is a retrospective study of 155 pediatric patients with duplex system ureterocele. The age of patients at the time of surgery ranged from 5 days to 17 years (median — 8.0 months). Intravesical ureterocele had 108 patients (69.8%), extravesical — 47 (30.2%).
Results. Complications occurred in 2 patients (1.3%), recurrence obstruction was in 1 case (0.6%). Ipsilateral vesicoureteral reflux after surgery had 112 patients (72.3%): in the upper pole — 51 cases (32.9%), in the lower pole — 32 (20.6%), in both ureters — 29 (18.7%). In the long-term period after transurethral incision of ureteroceles 97 patients (62.5%) needed reoperation due to infection and voiding dysfunction. Statistically significant risk factors associated with the need for reoperation were the presence of vesicoureteral reflux on the ureteroceles side and non-functioning upper pole of the kidney.
Conclusion. Transurethral incision of ureteroceles for duplex system ureterocele is a safe and effective minimally invasive method of primary resolving of the obstruction. Vesicoureteral reflux on the ureterocele side after surgery had 72.3% of patients; reoperation in the long term was necessary in 62.5% cases. The main risk factor reoperation is vesicoureteral reflux on the ureterocele side.
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##article.viewOnOriginalSite##About the authors
Vitaly I. Dubrov
2nd Сity Children’s Clinical Hospital
Author for correspondence.
Email: dubroff2000@mail.ru
Cand. Sci. (Med.), Head of the Department of Urology
Belarus, MinskAlexandr V. Strotsky
Belarusian State Medical University
Email: astrotsky@mail.ru
Dr. Sci. (Med.), Professor, Head of the Department of Urology
Belarus, MinskAleksey O. Shkutov
2nd Сity Children’s Clinical Hospital
Email: shkutov@yandex.ru
Urologist, Department of Urology
Russian Federation, MinskReferences
- Aikins K, Taghavi K, Grinlinton M, et al. Cystoscopic transurethral incision in simplex and duplex ureteroceles — is it the definitive procedure? J Pediatr Urol. 2019;15(5):560.e1-560.e 6. https://doi.org/10.1016/j.jpurol.2019.07.002.
- Gander R, Asensio M, Royo GF, Lloret J. Evaluation of the initial treatment of ureteroceles. Urology. 2016;89:113-117. https://doi.org/10.1016/j.urology.2015.11.025.
- Pohl HG. Recent advances in the management of ureteroceles in infants and children: why less may be more. Curr Opin Urol. 2011;21(4):322-327. https://doi.org/10.1097/MOU.0b013e328346d455.
- Kajbafzadeh A, Salmasi AH, Payabvash S, et al. Evolution of endoscopic management of ectopic ureterocele: a new approach. J Urol. 2007;177(3):1118-11123. https://doi.org/10.1016/j.juro.2006.11.001.
- Jesus LE, Farhat WA, Amarante ACM, et al. Clinical evolution of vesicoureteral reflux following endoscopic puncture in children with duplex system ureteroceles. J Urol. 2011;186(4):1455-1459. https://doi.org/10.1016/j.juro.2011.05.057.
- Castagnetti M, Vidal E, Burei M, et al. Duplex system ureterocele in infants: should we reconsider the indications for secondary surgery after endoscopic puncture or partial nephrectomy? J Pediatr Urol. 2013;9(1):11-16. https://doi.org/10.1016/j.jpurol.2012.06.016.
- Byun E, Merguerian PA. A meta-analysis of surgical practice patterns in the endoscopic management of ureteroceles. J Urol. 2006;176(4 Pt 2):1871-1877. https://doi.org/10.1016/S0022-5347(06)00601-X.
- Gomes J, Mendes M, Castro R, Reis A. Current role of simplified upper tract approach in the surgical treatment of ectopic ureteroceles: a single centre’s experience. Eur Urol. 2002;41(3):323-327. https://doi.org/10.1016/s0302-2838(02)00042-8.
- Shimada K, Matsumoto F, Matsui F. Surgical treatment for ureterocele with special reference to lower urinary tract reconstruction. Int J Urol. 2007;14(12):1063-1067. https://doi.org/10.1111/j.1442-2042.2007.01903.x.
- Cooper CS, Passerini-Glazel G, Hutcheson JC, et al. Long-term follow up of endoscopic incision of ureteroceles: intravesical versus extravesical. J Urol. 2000;164(3 Pt 2):1097-1099. https://doi.org/10.1097/00005392-200009020-00045.
- Castagnetti M, El-Ghoneimi A. Management of duplex system ureteroceles in neonates and infants. Nat Rev Urol. 2009;6(6):307-315. https://doi.org/10.1038/nrurol.2009.82.
- Hagg MJ, Mourachov PV, Snyder HM, et al. The modern endoscopic approach to ureterocele. J Urol. 2000;163(3):940-943.
- Singh SJ, Smith G. Effectiveness of primary endoscopic incision of ureteroceles. Pediatr Surg Int. 2001;17(7):528-531. https://doi.org/10.1007/s003830100586.
- Chertin B, de Caluwé D, Puri P. Is primary endoscopic puncture of ureterocele a long-term effective procedure? J Pediatr Surg. 2003;38(1):116-119. https://doi.org/10.1053/jpsu.2003.50023.
- Hodhod A, Jednak R, Khriguian J, El-Sherbiny M. Transurethral incision of ureterocele: Does the time of presentation affect the need for further surgical interventions? J Pediatr Urol. 2017;13(5):501.e1-501.e6. https://doi.org/10.1016/j.jpurol.2017.02.016.
- Monfort G, Guys JM, Coquet M, et al. Surgical management of duplex ureteroceles. J Pediatr Surg. 1992;27(5):634-638. https://doi.org/10.1016/0022-3468(92)90465-j.
- Boucher A, Cloutier J, Rousseau A, et al. Is an initial endoscopic treatment for all ureteroceles appropriate? J Pediatr Urol. 2013;9(3):339-343. https://doi.org/10.1016/j.jpurol.2012.04.009.
- Decter RM, Sprunger JK, Holland RJ. Can a single individualized procedure predictably resolve all the problematic aspects of the pediatric ureterocele? J Urol. 2001;165(6 Pt 2):2308-2310. https://doi.org/10.1097/00005392-200106001-00023.
- Sander JC, Bilgutay AN, Stanasel I, et al. Outcomes of endoscopic incision for the treatment of ureterocele in children at a single institution. J Urol. 2015;193(2):662-667. https://doi.org/10.1016/j.juro.2014.08.095.
- Adorisio O, Elia A, Landi L, et al. Effectiveness of primary endoscopic incision in treatment of ectopic ureterocele associated with duplex system. Urology. 2011;77(1):191-194. https://doi.org/10.1016/j.urology.2010.02.061.
- Castagnetti M, Cimador M, Sergio M, De Grazia E. Transurethral incision of duplex system ureteroceles in neonates: does it increase the need for secondary surgery in intravesical and ectopic cases? Br J Urol Int. 2004;93(9):1313-1317. https://doi.org/10.1111/j.1464-410X.2004.04861.x.
- Coplen DE, Austin PF. Outcome analysis of prenatally detected ureteroceles associated with multicystic dysplasia. J Urol. 2004;172(4 Pt 2):1637-1639. https://doi.org/10.1097/01.ju.0000138380.77747.7d
- Han MY, Gibbons MD, Belman AB, et al. Indications for nonoperative management of ureteroceles. J Urol. 2005;174(4 Pt 2):1652–1655. https://doi.org/10.1097/01.ju.0000175943.95989.41.
- Shankar KR, Vishwanath N, Rickwood AM. Outcome of patients with prenatally detected duplex system ureterocele; natural history of those managed expectantly. J Urol. 2001;165(4):1226–1228.
- Chertin B, Rabinowitz R, Pollack A, et al. Does prenatal diagnosis influence the morbidity associated with left in situ nonfunctioning or poorly functioning renal moiety after endoscopic puncture of ureterocele? J Urol. 2005;173(4):1349-1352. https://doi.org/10.1097/01.ju.0000155439.68182.b4.
- Husmann DA, Strand B, Ewalt D, et al. Management of ectopic ureterocele associated with renal duplication: a comparison of partial nephrectomy and endoscopic decompression. J Urol. 1999;162:1406-1409.
- Каганцов И.М., Сизонов В.В., Дубров В.И., и др. Лапароскопическая геминефруретерэктомия при удвоенной почке у детей // Урология. — 2017. — Т. 5. — С. 63–68. [Kagantsov IM, Sizonov VV, Dubrov VI, et al. Laparoscopic heminephrectomy for duplex kidney in children. Urology. 2017;5:63-68. (In Russ.)] https://doi.org/10.18565/urology.2017.5.69-74.
- Каганцов И.М., Сизонов В.В., Дубров В.И., и др. Уретероуретероанастомоз (уретеропиелоанастомоз) при удвоении верхних мочевыводящих путей у детей. Урология. 2018;2;69-74. [Kagantsov IM, Sizonov VV, Dubrov VI, et al. Ureteroureteroanastomosis (ureteropyeloanastomosis) for duplex system of the upper urinary tract in children. Urology. 2018;2:69-74. (In Russ.)] https://doi.org/10.18565/urology.2018.2.83-88.