Classical Article Evaluation of health-related quality of life the women with human papillomavirus-associated lesions of the cervical epithelium

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Abstract

Objective - to evaluate the health-related Quality of life the women with “lesser” abnormalities of cervical epithelium and patients with high grade squamous intraepithelial lesions (HSIL) associated with human papillomavirus (HPV) infection. Materials and methods. The investigation was performed 274 women of reproductive age, divided into two main groups: HPV infection (“lesser” abnormalities 202 patients and with HSIL - 20) and healthy women - 20. All the studied women of health-related quality of life by using the EQ-5D-5L. Results. Revealed a significant reduction in the level of health-related quality of life in the psychological and emotional components of the patients with “lesser” abnormalities of cervical epithelium and patients with HSIL associated with HPV infection (p<0.005). Conclusions. In most cases, patients with HPV infection was involved psychological component of health-related quality of life, anxiety, fear of further fertility affects the overall well-being of patients.

About the authors

E G Sycheva

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: el.bona@mail.ru
врач 117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

N M Nazarova

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

д-р мед. наук, вед. науч. сотр. 117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

O V Burmenskaya

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

д-р биол. наук, ст. науч. сотр. лаб. молекулярно-генетических методов 117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

V N Prilepskaya

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

д-р мед. наук, проф., зам. дир. 117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

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