Neuropsychological abnormalities in early-stage Parkinson’s disease
- 作者: Vereyutina I.1, Illarioshkin S.2, Zhuravleva E.3, Shikhkerimov R.1
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隶属关系:
- Neurological Department of Municipal Outpatients’ Clinic № 26, South Administrative District
- Research Center of Neurology
- Medical Department, Administration of President of the Russian Federation
- 期: 卷 6, 编号 2 (2012)
- 页面: 11-15
- 栏目: Original articles
- URL: https://journals.rcsi.science/2075-5473/article/view/124525
- DOI: https://doi.org/10.17816/psaic276
- ID: 124525
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全文:
详细
Comparative assessment of affective and cognitive abnormalities in different clinical forms of early-stage Parkinson’s disease (PD) was performed. In the majority of patients, cognitive decline of predominantly executive and neurodynamic type not reaching the dementia level was registered. The revealed cognitive disturbances prevailed in patients with an akinetic-rigid form of PD, while a trembling form turned out more benign from the viewpoint of its influence on the intellectual sphere. High prevalence of depression on early-stage PD was shown: depressive symptoms of various severities were observed in 84% examined patients. By analogy with cognitive decline, depression and anxiety at the debut of PD were significantly more frequent in patients with an akinetic-rigid form compared to a trembling phenotype. These data confirm that affective disturbances are very characteristic early (including premotor) manifestations of PD.
作者简介
I. Vereyutina
Neurological Department of Municipal Outpatients’ Clinic № 26, South Administrative District
编辑信件的主要联系方式.
Email: vereyutina@mail.ru
俄罗斯联邦, Moscow
Sergey Illarioshkin
Research Center of Neurology
Email: vereyutina@mail.ru
ORCID iD: 0000-0002-2704-6282
D. Sci. (Med.), Prof., Corr. Member of the Russian Academy of Sciences, Deputy Director, Head, Department for brain research
俄罗斯联邦, MoscowE. Zhuravleva
Medical Department, Administration of President of the Russian Federation
Email: vereyutina@mail.ru
俄罗斯联邦, Moscow
R. Shikhkerimov
Neurological Department of Municipal Outpatients’ Clinic № 26, South Administrative District
Email: vereyutina@mail.ru
俄罗斯联邦, Moscow
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