Application efficiency and effectiveness of Botulinum neurotoxin type A in complex treatment of patients with post – stroke spasticity in arm


如何引用文章

全文:

详细

Studying of efficiency of application botulinum neurotoxin type A in complex treatment 51 patients with poststroke spastic hemiparesis with mean time from stroke onset 33.8 months. It was observed severe spastisity (mean of scale of Ashworth – 3.3+1.0) at all patients in the neurologic status. Patients were divided in three groups. The first group (n = 14) received botulinum neurotoxin type A in a complex with standard restoring therapy (BtxA+SRT). In the second group (n = 18) the patients received BtxA+SRT in a complex with specialized functional training using device «ARMEO». The third group (n = 19) received only BtxA. Comparisons of scores on the MAS, AS, FIM and goniometry at baseline, week 5 and the 8-month follow-up are reviled the most considerable improvement of hand function in second group which received BtxA+SRT in a complex with specialized functional training using device «ARMEO». We believe that BtxA must use with complex therapy including the functional training of hand with device «ARMEO».

 

作者简介

E. Koneva

Federal State Institution “Treatment and Rehabilitation Center”, Moscow

编辑信件的主要联系方式.
Email: platonova@neurology.ru
俄罗斯联邦

E. Khatkova

Federal State Institution “Treatment and Rehabilitation Center”, Moscow

Email: platonova@neurology.ru
俄罗斯联邦

A. Albegova

Federal State Institution “Treatment and Rehabilitation Center”, Moscow

Email: platonova@neurology.ru
俄罗斯联邦

I. Sidyakina

Federal State Institution “Treatment and Rehabilitation Center”, Moscow

Email: platonova@neurology.ru
俄罗斯联邦

M. Makarova

Federal State Institution “Treatment and Rehabilitation Center”, Moscow

Email: platonova@neurology.ru
俄罗斯联邦

T. Shapovalenko

Federal State Institution “Treatment and Rehabilitation Center”, Moscow

Email: platonova@neurology.ru
俄罗斯联邦

K. Lyadov

Federal State Institution “Treatment and Rehabilitation Center”, Moscow

Email: platonova@neurology.ru
俄罗斯联邦

参考

  1. Беляев В.И. Спастика: оценка, лечение, гипотезы. М., 2003: 225.
  2. Епифанов В.А. Реабилитация больных, перенесших инсульт. М.: МЕДпресс-информ, 2006: 5.
  3. Кадыков А.С. Реабилитация после инсульта. М.: Миклош, 2003: 176.
  4. Кадыков А.С., Шахпаронова Н.В., Черникова Л.А. и др. Продолжительность двигательной и речевой реабилитации после инсульта. Неврол. вестн. 1994; т. XXVI: 3–4: 18–21.
  5. Ковальчук В.В., Скоромец А.А. Воздействие лечебной физической культуры на восстановление функций у больных после инсульта. Вопросы курортологии, физиотерапии и лечеб. физкультуры 2007; 4: 26–28.
  6. Применение токсина ботулизма типа А в клинической практике: Руководство для врачей / О.Р. Орлова, Н.Н. Яхно. М., 2001: 23.
  7. Парфенов В.А. Применение ботулинического токсина при пост- инсультной спастичности. Клин. геронтология 2001; т. 7: 3–4: 64–68.
  8. Aho K., Harmsen P., Hatano S., Marquardsen J., Smirnov V.E., Strasser T. Cerebrovascular disease in the community: results of a WHO collaborative study. Bull World Health Organ 1980; 58: 113–130.
  9. Bakheit A.M.O., Thilmann A.F., Ward A.B. at al. Рандомизированное двойное-слепое плацебо-контролируемое дозоранжирующее сравнительное исследование эффективности и безопасности трех доз ботулинического токсина типа А (Dysport) с плацебо при лечении постинсультной спастичности руки. Stroke 2000; 31: 2402–2406.
  10. Bhakta B.B., Cozens J.A., Bamford J.M., Chamberlain M.A. Use of botulinum toxin in stroke patients with severe upper limb spasticity. J. Neurol. Neurosurg. Psychiatry 1996; 61.
  11. Ferreira J.J., Pinto A.A., Crespo M., Ferro J.M., Castro-Caldas A. Botulinum toxin type A for the treatment of arm and hand spasticity in stroke patients. Clin. Rehabil 1997; 11: 3–7.
  12. Rogers D. Botulinum toxin A for spasticity-effect of over 400 treatments. Arch. Pharmacol 2002; 365: 36.
  13. Hesse S., Reiter F., Konard M., Jahnke M.T. Botulinum toxin type A and short-term electrical stimulation in the treatment of upper limb flexor spasticity after stroke: a randomized, double-blind, placebo-controlled trial . Clin. Rehabil 1998; 12: 381–388.
  14. Gowland C. Management of hemiplegic upper limb. Stroke Rehabilitation 1987: 217–245.
  15. Katrak P.H., Cole A.M.D., Poulos C.J., McCauley J.C.K. Objective assessment of spsaticity, strength and function with early exhibition of dantrolenesodium after cerebro-vascilar accident: a randomized, double- blind study. Arch. Med. Rehabil 1992; 73: 4–9.
  16. Reiter F., Danni M., Ceravolo M.G., Provinciali L. Disability changes after treatment of upper limb spasticity with botulinum toxin. J. Neurol. Rehab 1996;10: 47–52.
  17. Wade D.T., Wood V.A., Langton-Hewer R. Recovery after stroke: the first three months. Neurol. Neurosurg. Psychiatry 1985; 47: 7–13.
  18. Rogers D. Botulinum toxin A for spasticity-effect of over 400 treatments. Arch. Pharmacol. 2002; 365: 36.
  19. Wallesch C.-W., Maes E., Lecomte P., Bartels C. Cost-effectiveness of botulinum toxin type A injection in patients with spasticity following stroke: a German perspective. Eur. J. Nerol. 1997; 4, Suppl. 2: 53–57.
  20. Shu-Fen Sun, Chien-Wei Hsu, Chiao-Wen Hwang, Pei-Te Hsu, Jue- Long Wang and Chia-Lin Yang. Application of Combined Botulinum Toxin Type A and Modified Constraint-Induced Movement Therapy for an Individual With Chronic Upper-Extremity Spasticity After Stroke. PHYS THER ; 86: 10, October 2006: 1387–1397.
  21. Ozcakir S., Sivrioglu К. Botulinum Toxin in Poststroke Spasticity. Clin. Medicine & Research; 5: 2: 132–138.

版权所有 © Koneva E.S., Khatkova E.S., Albegova A.V., Sidyakina I.V., Makarova M.R., Shapovalenko T.V., Lyadov K.V., 2010

Creative Commons License
此作品已接受知识共享署名 4.0国际许可协议的许可
##common.cookie##