Poststroke Asthenic Disorder

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Abstract

Asthenic disorders are seen in approximately half of poststroke patients. The mechanisms underlying poststroke asthenia (PSA) are related to brain connectome damage, as well as neuroinflammatory and neuroendocrine mechanisms. PSA is associated with a lack of energy, lassitude, and fatigue that do not improve after rest or sleep; it is differentiated from depression, apathy, and daytime drowsiness. Risk factors for PSA include female gender, anxiety and depressive disorders, severe neurological deficit, sleep disorders, diabetes etc. Treatment of PSA includes cognitive behavioral therapy graded physical activity, and pharmacotherapy.

About the authors

Mansur A. Kutlubaev

Bashkir State Medical University

Author for correspondence.
Email: mkmed@mail.ru
ORCID iD: 0000-0003-1001-2024

D. Sci. (Med.), Assoc. Prof., Head, Department of Neurology

Russian Federation, Ufa

Albina I. Akhmetova

Republican Clinical Hospital named after G.G. Kuvatov

Email: zolot55@mail.ru
ORCID iD: 0000-0002-9769-869X

Attending Neurologist

Russian Federation, Ufa

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