Ischemic Stroke and COVID-19 Infection: an Analysis of Treatment Outcomes in Patients who Underwent Endovascular Thrombectomy

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Abstract

Aim. This study aimed to compare and evaluate treatment outcomes in groups of ischemic stroke patients with or without COVID-19 infection who underwent endovascular thrombectomy (EVT).

Materials and methods. We conducted a retrospective analysis of 817 case records of IS patients aged 25 to 99 years with confirmed thrombotic occlusion of cerebral arteries and subsequent EVT who were treated in regional vascular centers in St. Petersburg from January 1, 2021

to December 31, 2021.

Results. Patients without COVID-19 had favorable outcome more often than patients with confirmed COVID-19 (35.0% vs. 7.3%, p < 0.001); mortality rate was 30% vs. 52%, respectively (p < 0.001).

Conclusions. Intercurrent COVID-19 significantly worsened prognosis and increased risk of death in ischemic stroke patients who underwent EVT.

About the authors

Alexander I. Yakovlev

Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine

Author for correspondence.
Email: yakovlevai92@yandex.ru
ORCID iD: 0000-0001-7648-4388

neurologist

Russian Federation, Saint-Petersburg

Igor A. Voznyuk

Pavlov First Saint Petersburg State Medical University Russia; Immanuel Kant Baltic Federal University

Email: yakovlevai92@yandex.ru
ORCID iD: 0000-0002-0340-4110

D. Sci. (Med.), Professor

Russian Federation, Saint-Petersburg; Kaliningrad

Tatiana V. Kharitonova

National Society of Neurosonology and Cerebral Hemodynamics

Email: yakovlevai92@yandex.ru
ORCID iD: 0000-0003-4021-9421

secretary, Board of the Association

Russian Federation, Saint-Petersburg

Alexander V. Savello

Immanuel Kant Baltic Federal University

Email: yakovlevai92@yandex.ru
ORCID iD: 0000-0002-1680-6119

D. Sci. (Med.), Professor, Deputy Head, Department of neurosurgery

Russian Federation, Kaliningrad

Mariia V. Prokhorova

Pavlov First Saint Petersburg State Medical University Russia

Email: yakovlevai92@yandex.ru
ORCID iD: 0000-0003-3412-0038

neurologist, Department of neurology for patients with acute cerebrovascular accident of the clini

Russian Federation, Saint-Petersburg

Sergey V. Kolomentsev

Immanuel Kant Baltic Federal University; Kirov Military Medical Academy

Email: yakovlevai92@yandex.ru
ORCID iD: 0000-0002-3756-6214

Cand. Sci. (Med.), senior researcher, Head, Neurological department, Clinic of Nervous Diseases

Russian Federation, Kaliningrad; Saint-Petersburg

Nadezhda А. Tsurikova

Regional Children’s Clinical Hospital

Email: yakovlevai92@yandex.ru
ORCID iD: 0000-0002-3946-430X

Cand. Sci. (Med.), pediatrician, Neurological department

Russian Federation, Rostov-on-Don

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Copyright (c) 2024 Yakovlev A.I., Voznyuk I.A., Kharitonova T.V., Savello A.V., Prokhorova M.V., Kolomentsev S.V., Tsurikova N.А.

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