Differential diagnosis of amiodarone-induced thyrotoxicosis in a patient with atrial fibrillation and agranulocytosis on the background of thyrostatic therapy. Case report
- Authors: Zherebchikova K.Y.1, Bubnov D.S.2, Ermolaeva A.S.1, Soltakhanova M.O.1, Sych Y.P.1, Ezhov M.V.2, Fadeev V.V.1
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Affiliations:
- Sechenov First Moscow State Medical University (Sechenov University)
- Myasnikov Research Institute of Clinical Cardiology, Chazov National Medical Research Center of Cardiology
- Issue: Vol 26, No 1 (2024): Cardiology and Nephrology
- Pages: 7-11
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/256814
- DOI: https://doi.org/10.26442/20751753.2024.1.202665
- ID: 256814
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Abstract
Atrial fibrillation is the most common heart rhythm disorder in patients with chronic heart failure. One of the most effective antiarrhythmic drugs for the treatment and prevention of a wide range of supraventricular and ventricular tachyarrhythmia is amiodarone. In the group of patients with paroxysmal atrial fibrillation and low left ventricular ejection fraction, it is the drug of choice when conducting a „rhythm control“ strategy. Patients receiving amiodarone often develop an adverse event – amiodarone-induced thyrotoxicosis, which exacerbates the course of cardiovascular pathology. In this article, we consider a clinical case of amiodarone-induced thyrotoxicosis in a 30-year-old patient with dilated cardiomyopathy and agranulocytosis that developed against the background of thyrostatic therapy.
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##article.viewOnOriginalSite##About the authors
Kristina Yu. Zherebchikova
Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: k.y.zherebchikova@gmail.com
ORCID iD: 0000-0003-0292-5907
Аssistant
Russian Federation, MoscowDmitry S. Bubnov
Myasnikov Research Institute of Clinical Cardiology, Chazov National Medical Research Center of Cardiology
Email: k.y.zherebchikova@gmail.com
ORCID iD: 0000-0003-1538-2761
Res. Assist.
Russian Federation, MoscowAlexandra S. Ermolaeva
Sechenov First Moscow State Medical University (Sechenov University)
Email: k.y.zherebchikova@gmail.com
ORCID iD: 0000-0002-6471-8252
Endocrinologist
Russian Federation, MoscowMadina O. Soltakhanova
Sechenov First Moscow State Medical University (Sechenov University)
Email: k.y.zherebchikova@gmail.com
ORCID iD: 0009-0004-2816-0943
Student
Russian Federation, MoscowYulia P. Sych
Sechenov First Moscow State Medical University (Sechenov University)
Email: k.y.zherebchikova@gmail.com
ORCID iD: 0000-0002-7000-0095
Cand. Sci. (Med.)
Russian Federation, MoscowMarat V. Ezhov
Myasnikov Research Institute of Clinical Cardiology, Chazov National Medical Research Center of Cardiology
Email: k.y.zherebchikova@gmail.com
ORCID iD: 0000-0002-1518-6552
D. Sci. (Med.), Department Head
Russian Federation, MoscowValentin V. Fadeev
Sechenov First Moscow State Medical University (Sechenov University)
Email: k.y.zherebchikova@gmail.com
ORCID iD: 0000-0002-2504-7468
D. Sci. (Med.), Prof., Corr. Memb. RAS, Department Head
Russian Federation, MoscowReferences
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