Stone-dissolving therapy of coral calculus

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Abstract

Uric acid stones make up about 10% of the total nephrolithiasis structure. Low urine pH is the primary risk factor for the formation of such stones. Additional factors include a high content of urate in the urine and small diuresis. To dissolve uric acid stones, oral medications are used to increase urine pH. According to literary sources, the litholysis of stones against the background of citrate therapy is achieved within 1.5-6 months or more. At the same time, data on the size of which stones can be dissolved using citrates is very limited. The analysis of the use of stone-dissolving therapy by the course of oral medication with citrate mixtures in 2 patients with coral-shaped (K-4) kidney stones treated in the Regional Urological Center on the basis of Sverdlovsk Regional Clinical Hospital №1 in 2018 has been carried out. The possibility of using litholytic therapy to dissolve large urate kidney stones is presented.

About the authors

Igor V. Bazhenov

Ural State Medical University; Sverdlovsk Regional Clinical Hospital №1

Email: biv@okb1.ru
D. Sci. (Med.) Ekaterinburg, Russia

Alexander V. Zyryanov

Ural State Medical University

Email: zav1965@mail.ru
D. Sci. (Med.) Ekaterinburg, Russia

Viktor O. Danilov

Sverdlovsk Regional Clinical Hospital №1

Email: daniloffviktor@gmail.com
urologist Ekaterinburg, Russia

Ekaterina S. Philippova

Ural State Medical University; Sverdlovsk Regional Clinical Hospital №1

Email: filippova.cat@yandex.ru
канд. мед. наук, доц. каф. урологии Ekaterinburg, Russia

Albert A. Makaryan

Ural State Medical University

Cand. Sci. (Med.) Ekaterinburg, Russia

Pavel D. Bessonov

Sverdlovsk Regional Clinical Hospital №1

Email: p-bessonov@mail.ru
врач-уролог Ekaterinburg, Russia

Sergey A. Burcev

Sverdlovsk Regional Clinical Hospital №1

urologist, Cand. Sci. (Med.) Ekaterinburg, Russia

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