Mini-gastric bypass: is it a new operation of choice in metabolic surgery in diabetes mellitus type 2?

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Abstract

Relevance. The prevalence of diabetes mellitus type 2 (DM2) and obesity takes a pandemic form. Substantial progress had been made in pharmacotherapy for these disorders but there still are patients who develop complications caused by these disorders. A positive effect of metabolic surgery in patients with DM2 and obesity is well known. The review discusses the influence of mini-gastric bypass (MGP) on DM2 course and the possibility of DM2 remission. Materials and methods. A literature search was performed in Medline, Scopus, Web of Sciences, and RSCI databases with the use of key words: mini gastric bypass, single anastomosis gastric bypass, omega loop gastric bypass, loop gastric bypass, MGB, LMGB, мини-гастрошунтирование, гастрошунтирование с одним анастомозом. The search was performed in English and Russian. The search was performed for publications over the years 2001-2019. Results. A considerable improvement in DM2 course after MGP was shown. In 75-90% of cases DM2 remission could be achieved. The acquired results were not different and in some cases were better than those of traditional gastric bypass and were much better than results of sleeve gastrectomy. An increased risk of complications development was found neither in early nor in late postoperative period. Conclusion. MGB appears an effective bariatric operation and can be an operation of choice in patients with DM2 and obesity. Nevertheless it is reasonable to perform more prospective randomized controlled trials to determine additional metabolic advantages of MGB.

About the authors

Igor A. Sklyanik

Endocrinology Research Centre

Email: *sklyanik.igor@gmail.com
Endocrinologist Moscow, Russia

Andrey V. Karmadonov

Endocrinology Research Centre

Email: a.karmadonov@bk.ru
and. Sci. (Med.), Surgeon Moscow, Russia

Marina V. Shestakova

Endocrinology Research Centre

Email: nephro@endocrincentr.ru
Acad. RAS, D. Sci. (Med.), Full Prof Moscow, Russia

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