Neopterin is a biomarker of chronic heart failure (review of modern literature)
- Authors: Alieva A.M.1, Pinchuk T.V.1, Voronkova K.V.1,2,3,4, Shnakhova L.M.5, Ettinger O.A.1, Akhmedova M.F.6, Valiev R.K.7, Kalova M.R.1, Gasanova E.T.1, Nikitin I.G.1
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Affiliations:
- Pirogov Russian National Research Medical University
- Central Clinical Hospital of the Russian Academy of Sciences
- Association of Epileptologists and Patients
- Center for the Study of Problems of a Falling Patient in Medicine
- Sechenov First Moscow State Medical University (Sechenov University)
- Multipurpose Medical Center “AKFA Medline”
- Loginov Moscow Clinical Scientific and Practical Center
- Issue: Vol 23, No 10 (2021)
- Pages: 756-759
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/96684
- DOI: https://doi.org/10.26442/20751753.2021.10.201113
- ID: 96684
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Abstract
Inflammation plays a role in the pathogenesis of heart failure. Neopterin, pteridine, synthesized mainly by activated macrophages, is a marker of inflammation, activation of the immune system, and an active participant in cardiovascular disease. Measuring neopterin levels can help track the evolution of specific inflammatory conditions. In addition, neopterin was associated with cardiac dysfunction after cardiac surgery and improved the accuracy of predicting the risk of postoperative cardiac dysfunction. In this review, we provide current insights into neopterin and its relationship to heart failure.
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##article.viewOnOriginalSite##About the authors
Amina M. Alieva
Pirogov Russian National Research Medical University
Author for correspondence.
Email: amisha_alieva@mail.ru
ORCID iD: 0000-0001-5416-8579
Cand. Sci. (Med.), Pirogov Russian National Research Medical University
Russian Federation, MoscowTatiana V. Pinchuk
Pirogov Russian National Research Medical University
Email: amisha_alieva@mail.ru
ORCID iD: 0000-0002-7877-4407
Cand. Sci. (Med.), Pirogov Russian National Research Medical University
Russian Federation, MoscowKira V. Voronkova
Pirogov Russian National Research Medical University; Central Clinical Hospital of the Russian Academy of Sciences; Association of Epileptologists and Patients; Center for the Study of Problems of a Falling Patient in Medicine
Email: kiravoronkova@yandex.ru
D. Sci. (Med.), Prof., Pirogov Russian National Research Medical University, Central Clinical Hospital of the Russian Academy of Sciences, Association of Epileptologists and Patients, Center for the Study of Problems of a Falling Patient in Medicine
Russian Federation, MoscowLidiia M. Shnakhova
Sechenov First Moscow State Medical University (Sechenov University)
Email: shnakhova_l_m@staff.sechenov.ru
doctor
Russian Federation, MoscowOlga A. Ettinger
Pirogov Russian National Research Medical University
Email: olga-oett@mail.ru
ORCID iD: 0000-0002-1237-3731
Cand. Sci. (Med.), Pirogov Russian National Research Medical University
Russian Federation, MoscowMadina F. Akhmedova
Multipurpose Medical Center “AKFA Medline”
Email: drmadina@yandex.ru
Cand. Sci. (Med), AKFA Medline
Uzbekistan, TashkentRamiz K. Valiev
Loginov Moscow Clinical Scientific and Practical Center
Email: Radiosurgery@bk.ru
ORCID iD: 0000-0003-1613-3716
Cand. Sci. (Med.), Loginov Moscow Clinical Scientific and Practical Center
Russian Federation, MoscowMarina R. Kalova
Pirogov Russian National Research Medical University
Email: marina717717@mail.ru
ORCID iD: 0000-0002-8949-4523
Graduate Student, Pirogov Russian National Research Medical University
Russian Federation, MoscowElvina T. Gasanova
Pirogov Russian National Research Medical University
Email: amisha_alieva@mail.ru
Graduate Student, Pirogov Russian National Research Medical University
Russian Federation, MoscowIgor G. Nikitin
Pirogov Russian National Research Medical University
Email: igor.nikitin.64@mail.ru
ORCID iD: 0000-0003-1699-0881
D. Sci. (Med.), Prof., Pirogov Russian National Research Medical University
Russian Federation, MoscowReferences
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