Vitamin D deficiency in benign paroxysmal positional vertigo

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Abstract

Aim. To assess the level of vitamin D (D3) in patients with benign paroxysmal positional vertigo (BPPV).

Materials and methods. The study included 25 patients. The control group consisted of 30 people, comparable in age with the main group, without BPPV. All patients included in the study underwent a standard examination of the vestibular sphere, which compised the Head impulse test, the Fukuda test, the Shaking test, the Dix–Holpike and Maclura–Pagnini test. Hydroxyvitamin D levels were analyzed by enzyme immunoassay. In the study of the psychological sphere, the following questionnaires were used: Dizziness Handicap Inventory, Beck Depression Scale, Spielberger–Khanin Anxiety Scale, TAS-26 alexithymia scale.

Results. The average level of hydroxyvitamin D among patients was 19.65±8.6 ng/ml, which corresponds to a deficiency of vitamin D, in the control group, vitamin D3 was within the reference values (30–100 ng/ml) and amounted to 33.78±10.7 ng/ml (p<0.001). There is a negative correlation between the level of hydroxyvitamin D and the age of the patients. There is a correlation (Spearman's criterion -0.463254, p<0.001) between the frequency of recurrence of BPPV and a decrease in the level of hydroxyvitamin D.

Conclusion. Vitamin D deficiency prevails among patients with BPPV.

About the authors

Anna S. Bedenko

Sechenov First Moscow State Medical University (Sechenov University)

Email: luda6917@yandex.ru

Graduate Student

Russian Federation, Moscow

Ludmila M. Antonenko

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: luda6917@yandex.ru
ORCID iD: 0000-0002-4400-8632

D. Sci. (Med.), Prof.

Russian Federation, Moscow

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