Impact of different medication groups on drug-induced seizures risk

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Abstract

One of the reasons for the development of epileptic seizures (ES) is the effect of certain drugs. Drug-induced ES and status epilepticus can also develop due to administration or withdrawal of a large number of drugs. The most common drug-induced ES are associated with the use of antidepressants, antiepileptic drugs, antibiotics, antitumor drugs, opioid analgesics, anesthetics, etc. Awareness and adequate assessment of the potential risk of the development of drug-induced ES, monitoring and correction of factors that determine and increase the risk of drug-induced ES, as well as the withdrawal or change of drugs that potentially cause ES, are the most important preventive measures to prevent the development of drug-induced ES and status epilepticus. Key words: epileptic seizures, drug-induced seizures, adverse drug reactions. For citation: Ostroumova Т.М., Akimova E.S., Kochetkov A.I., Ostroumova O.D. Impact of different medication groups on drug-induced seizures risk. Consilium Medicum. 2020; 22 (5): 98-105. DOI: 10.26442/20751753.2020.5.200001

About the authors

Tatiana M. Ostroumova

Sechenov First Moscow State Medical University (Sechenov University)

канд. мед. наук, ассистент каф. нервных болезней и нейрохирургии Института клинической медицины Moscow, Russia

Elizaveta S. Akimova

Yevdokimov Moscow State University of Medicine and Dentistry

студентка 6-го курса лечебного фак-та Moscow, Russia

Aleksei I. Kochetkov

Russian Medical Academy of Continuous Professional Education

канд. мед. наук, доц. каф. терапии и полиморбидной патологии Moscow, Russia

Olga D. Ostroumova

Russian Medical Academy of Continuous Professional Education

Email: ostroumova.olga@mail.ru
д-р мед. наук, проф., зав. каф. терапии и полиморбидной патологии Moscow, Russia

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