A CONTEMPORARY VIEW ON DIAGNOSIS AND TREATMENT OF MENIERE’S DISEASE

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Abstract

Meniere's disease is an idiopathic condition of the inner ear, characterized by episodic attacks of vertigo, aural fullness, tinnitus and a sensorineural hearing loss. Meniere's disease has a progressive course despite of the treatment. This implies that the pathogenesis of Meniere's disease is not well understood and the treatment methods used are ineffective. The aim of this review is to summarize the contemporary theories of the pathogenesis of Meniere's disease, as well as to analyze different methods of diagnosis and treatment.

About the authors

Sergei la. Kosyakov

Russian Medical Academy of Continuous Professional Education

Email: serkosykov@yandex.ru
д-р мед. наук, проф., зав. каф. оториноларингологии Moscow, Russia

Kseniia N. Bgantceva

Russian Medical Academy of Continuous Professional Education

аспирант каф. оториноларингологии Moscow, Russia

Aleksandr V. Gunenkov

Russian Medical Academy of Continuous Professional Education

канд. мед. наук, доц. каф. оториноларингологии Moscow, Russia

Ekaterina V. Pchelenok

Russian Medical Academy of Continuous Professional Education

ассистент каф. оториноларингологии Moscow, Russia

References

  1. Gurkov R, Pyyko I, Zou J, Kentala E. What is Meniere’s disease? A contemporary re-evaluation of endolymphatic hydrops. J Neurol 2016; 263 (Suppl. 1): 71-81.
  2. Friberg U, Stahle J, Svedberg A. The natural course of Meniere's disease. Acta Otolaryngol 1984; 406 (Suppl.): 72-7.
  3. Moffat DA, Ballagh RH. Meniere's disease. In: Kerr AG, Booth JB, eds. Scott-Brown's otolaryngology. 6th ed. Oxford: Butterworth-Heinemann, 1997.
  4. Silverstein H, Smouha E, Jones R. Natural history versus surgery for Meniere's disease. Otolaryngol Head Neck Surg 1989; 100: 6-16.
  5. Pyykko I, Nakashima T, Yoshida T, Zou J, Naganawa S. Meniere’s disease: a reappraisal supported by a variable latency of symptoms and the MRI visualisation of endolymphatic hydrops. BMJ Open 2013; 3 (2).
  6. AAO-HNS Committee on hearing and equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere’s disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc. Otolaryngol Head Neck Surg 1995; 113 (3): 181-5.
  7. Lopez-Escamez JA, Carey J, Chung WH et al. Diagnostic criteria for Meniere’s disease. J Vestib Res 2015; 25 (1): 1-7.
  8. Plontke SK, Gurkov R. Meniere’s Disease. Laryngo-Rhino-Otol 2015; 94 (8): 530-54.
  9. Hallpike CS, Cairns H. Observations on the pathology of Meniere's syndrome. Proc R Soc Med 1938;31:1317-36.
  10. Yamakawa K. Uber die pathologische Veranderung bei einem Meniere's-Kranken. Proceedings of 42nd Annual Meeting Oto-Rhino-Laryngol Soc Japan. J Otolaryngol Soc Jpn 1938; 4: 2310-2.
  11. Merchant SN, Rauch SD, Nadol JB Jr. Meniere’s disease. Eur Arch Otorhinolaryngol 1995; 252 (2): 63-75
  12. Nakashima T, Naganawa S, Pyykko I et al. Grading of endolymphatic hydrops using magnetic resonance imaging. Acta Otolaryngol 2009; 560: 5-8.
  13. Morita N, Kariya S, Farajzadeh Deroee A et al. Membranous labyrinth volumes in normal ears and Meniere disease: a three-dimensional reconstruction study. Laryngoscope 2009; 119 (11): 2216-20.
  14. Hannigan IP, Welgampola MS, Watson Shaun RD. Dissociation of caloric and head impulse tests: a marker of Meniere’s disease. J Neurol 2019; 266 (12): 3162.
  15. McCaslin DL, Rivas A, Jacobson GP, Bennett ML. The dissociation of video head impulse test (vHIT) and bithermal caloric test results provide topological localization of vestibular system impairment in patients with "definite" Meniere’s disease. Am J Audiol 2015; 24 (1): 1-10.
  16. McGarvie LA, Curthoys IS, MacDougall HG, Halmagyi GM. What does the dissociation between the results of video head impulse versus caloric testing reveal about the vestibular dysfunction in Meniere’s disease? Acta Otolaryngol 2015; 135 (9): 859-65.
  17. Rubin F, Simon F, Verillaud B et al. Comparison of video head impulse test and caloric re ex test in advanced unilateral de nite Meniere’s disease. Eur Ann Otorhinolaryngol Head Neck Dis 2018; 135 (3): 167-9.
  18. Ruth R, Lambert P Comparison of tympanic membrane to promontory electrode recordings of elect-rocochleographic responses in patients with Meniere’s disease. Otolaryngol Head Neck Surg 1989; 100: 546-52.
  19. Ng M, Srireddy S, Horlbeck DM, Niparko JK. Safety and patient experience with transtympanic elect-rocochleography. Laryngoscope 2001; 111: 792-5.
  20. Nakashima T, Naganawa S, Sugiura M et al. Visualization of endolymphatic hydrops in patients with Meniere’s disease. Laryngoscope 2007; 117: 415-20.
  21. Pyykko I, Zou J, Poe D. Magnetic resonance imaging of the inner ear in Meniere’s disease. Otolaryngol Clin North Am 2010; 15: 353-63.
  22. Gurkov R, Flatz W, Louza J et al. In vivo visualized endolymphatic hydrops and inner ear functions in patients with electrocochleographically confirmed Meniere’s disease. Otol Neurotol 2012; 33: 1040-5.
  23. Zou J, Pyykko I, Bjelke B et al. Communication between the perilymphatic scalae and spiral ligament visualized by in vivo MRI. Audiol Neuro-Otol 2005; 10 (3): 145-52.
  24. Louza J, Krause E, Gurkov R. Audiologic evaluation of Meniere’s disease patients one day and one week after intratympanic application of gadolinium contrast agent: our experience in sixty-five patients. Clin Otolaryngol 2013; 38 (3): 262-6.
  25. Louza J, Krause E, Gurkov R. Hearing function after intratympanic application of gadolinium-based contrast agent: a long-term evaluation. Laryngoscope 2015; 125 (10): 2366-70.
  26. Louza JP, Flatz W, Krause E, Gurkov R. Short-term audiologic effect of intratympanic gadolinium contrast agent application in patients with Menie're’s disease. Am J Otolaryngol 2012; 33 (5): 533-7.
  27. Nakada T, Yoshida T, Suga K. Endolymphatic space size in patients with vestibular migraine and Menie're’s disease. J Neurol 2014; 261: 2019-84.
  28. Gurkov R, Kantner C, Strupp M. Endolymphatic hydrops in patients with vestibular migraine and auditory symptoms. Eur Arch Otorhinolaryngol 2014; 271: 2661-7.
  29. Ruckenstein MJ, Harrison RV. Cochlear pathology in Meniere's disease. In: Harris JP, ed. Meniere's disease. The Hague: Kugler Publications, 1999: 195-202.
  30. Naganawa S, Yamazaki M, Kawai H et al. Visualization of endolymphatic hydrops in Meniere's disease with single-dose intravenous gadolinium-based contrast media using heavily T(2)-weighted 3D-FLAIR. Magn Reson Med Sci 2010; 9 (4): 237-42.
  31. Naganawa S, Satake H, Kawamura M et al. Separate visualization of endolymphatic space, perilymphatic space and bone by a single pulse sequence; 3D-inversion recovery imaging utilizing real reconstruction after intratympanic Gd-DTPA administration at 3 Tesla. Eur Radiol 2008; 18 (5): 920-4.
  32. Jerin C, Krause E, Ertl-Wagner B, Gurkov R. Longitudinal assessment of endolymphatic hydrops with contrast-enhanced magnetic resonance imaging of the labyrinth. Otol Neurotol 2014; 35 (5): 880-3.
  33. Gurkov R, Flatz W, Ertl-Wagner B, Krause E. Endolymphatic hydrops in the horizontal semicircular canal: a morphologic correlate for canal paresis in Meniere's disease. Laryngoscope 2013; 123 (2): 503-6.
  34. Gurkov R, Flatz W, Louza J et al. In vivo visualization of endolyphatic hydrops in patients with Meniere’s disease: correlation with audiovestibular function. Eur Arch Otorhinolaryngol 2011; 268 (12): 1743-8.
  35. Gurkov R, Flatz W, Louza J et al. Herniation of the membranous labyrinth into the horizontal semicircular canal is correlated with impaired caloric response in Meniere’s disease. Otol Neurotol 2012; 33 (8): 1375-9.
  36. Naganawa S, Nakashima T. Visualization of endolymphatic hydrops with MR imaging in patients with Meniere’s disease and related pathologies: current status of its methods and clinical significance. Jpn J Radiol 2014; 32 (4): 191-204.
  37. Nakashima T, Naganawa S, Teranishi M et al. Endolymphatic hydrops revealed by intravenous gadolinium injection in patients with Meniere’s disease. Acta Otolaryngol 2010; 130 (3): 338-43.
  38. Fiorino F, Pizzini FB, Beltramello A et al. Reliability of magnetic resonance imaging performed after intratympanic administration of gadolinium in the identification of endolymphatic hydrops in patients with Meniere’s disease. Otol Neurotol 2011; 32 (3): 472-7.
  39. Coelho DH, Lalwani AK. Medical management of Meniere's disease. Laryngoscope 2008; 118: 1099-108.
  40. Wright T. Meniere's disease. BMJ Clin Evid. 2006; pii: 0505. Published online
  41. Hussain K1, Murdin L, Schilder AG. Restriction of salt, caffeine and alcohol intake for the treatment of Meniere's disease or syndrome. Cochrane Database Syst Rev 2018; 12: CD012173.
  42. Storper IS, Spitzer JB, Scanlan M. Use of glycopyrrolate in the treatment of Meniere's disease. Laryngoscope 1998; 108: 1442-5.
  43. James AL, Burton MJ. Betahistine for Meniere's disease or syndrome. In: The Cochrane Library: Issue 4, 2005.
  44. Salami A, Dellepiane M, Tinelle E et al. Double blind study between betahistine hydrochloride and placebo in the treatment of Meniere's syndromes. Valsalva 1984; 60: 302-12.
  45. Schmidt JT, Huizing EH. The clinical drug trial in Meniere's disease with emphasis on the effect of betahistine SR. Acta Otolaryngol 1992; 497 (Suppl.): 1-89.
  46. Fleiss JL. The crossover study. In: The design and analysis of clinical experiments. Chichester: Wiley, 1984
  47. Okamato K, Hazeyama F, Taira T et al. Therapeutic results of betahistine in Meniere's disease with statistical analysis. Iryo 1968; 22: 650-66.
  48. Ricci V, Sittoni V, Nicora M. Efficacy and safety of betahistine hydrochloride versus placebo in Meniere's disease. Riv Ital Ornitolog Audiolog Foniat 1987; 7: 347-50.
  49. Burkin A. Betahistine treatment of Meniere's syndrome. Clin Med 1967; 74: 41-8.
  50. Mira E, Guidetti G, Ghilardi L et al. Betahistine dihydrochloride in the treatment of peripheral vestibular vertigo. Eur Arch Otorhinolaryngol 2003; 260: 73-7.
  51. Murdin L, Hussain K, Schilder AG. Betahistine for symptoms of vertigo. Cochrane Database Syst Rev 2016; 21: CD010696.
  52. Gurkov R, Flatz W, Keeser D et al. Effect of standard-dose Betahistine on endolymphatic hydrops: an MRI pilot study. Eur Arch Otorhinolaryngol 2013; 270 (4): 1231-5.
  53. Adrion C, Fischer CS, Wagner J et al. Efficacy and safety of betahistine treatment in patients with Meniere's disease: primary results of a long term, multicentre, double blind, randomised, placebo controlled, dose defining trial (BEMED trial). BMJ 2016; 352: h6816.
  54. Diamond C, O'Connell DA, Hornig JD, Liu R. Systematic review of intratympanic gentamicin in Meniere's disease. J Otolaryngol 2003; 32: 351-61.
  55. Chia SH, Gamst AC, Anderson JP, Harris JP. Intratympanic gentamicin therapy for Meniere's disease: a metaanalysis. Otol Neurotol 2004; 25: 544-52.
  56. Casani AP, Piaggi P, Cerchiai N et al. Intratympanic treatment of intractable unilateral Meniere disease: gentamicin or dexamethasone? A randomized controlled trial. Otolaryngol Head Neck Surg 2012;146:430-7.
  57. Longridge NS, Mallinson AI. Low-dose intratympanic gentamicin treatment for dizziness in Meniere's disease. J Otolaryngol 2000; 29: 35-9.
  58. Quaranta A, Scaringi A, Aloidi A et al. Intratympanic therapy for Meniere's disease: effect of administration of low concentration of gentamicin. Acta Otolaryngol 2001; 121: 387-92.
  59. Minor LB. Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy. Am J Otol 1999; 20: 209-19.
  60. Ozturk K, Ata N. Intratympanic mixture gentamicin and dexamethasone versus dexamethasone for unilateral Meniere's disease. Am J Otolaryngol 2019; 40 (5): 711-4.
  61. Stokroos R, Kingma H. Selective vestibular ablation by intratympanic gentamicin in patients with unilateral active Meniere's disease: a prospective, double-blind, placebo-controlled, randomized clinical trial. Acta Otolaryngol 2004; 124: 172-5.
  62. Postema RJ, Kingma CM, Wit HP. Intratympanic gentamicin therapy for control of vertigo in unilateral Meniere's disease: a prospective, double-blind, randomized, placebo-controlled trial. Acta Otolaryngol 2008;128:876-80.
  63. Garduno-Anaya MA, Couthino De Toledo H, Hinojosa-Gonzalez R. Dexamethasone inner ear perfusion by intratympanic injection in unilateral Meniere's disease: a two-year prospective, placebo-controlled, double-blind, randomized trial. Otolaryngol Head Neck Surg 2005; 133: 285-94.
  64. Phillips JS, Westerberg B. Intratympanic steroids for Meniere’s disease or syndrome. Cochrane Database Syst Rev 2011; 7: CD008514.
  65. A 1-year safety study of OTO-104 in subjects with unilateral Meniere’s disease Located in United Kingdom. https://clinicaltrials.gov/ct2/show/ NCT02265393
  66. Sevilla C, Goody J, Baguley DM, Kasbekar AV. Aural fullness and transtympanic ventilation tubes in Meniere's disease: a scoping review. J Laryngol Otol 2019; 133 (6): 450-6.
  67. Russo FY, Nguyen Y, De Seta D et al. Meniett device in Meniere’s disease: Randomized, doubleblind, placebo-controlled multicenter trial. Laryngoscope 2017; 127 (2): 470-5.
  68. Saeed SR. Fortnightly review: diagnosis and treatment of Meniere's disease. BMJ 1998; 316:368-72.
  69. Thomsen J, Bonding P, Becker B et al. The non-specific effect of endolymphatic sac surgery in treatment of Meniere’s disease: a prospective, randomized controlled study comparing “classic” endolymphatic sac surgery with the insertion of a ventilating tube in the tympanic membrane. Acta Otolaryngol 1998;118: 769-73.
  70. Morel N, Dumas G, Nguyen DQ, Mohr E. Vestibular neurotomy versus chemical labyrinthectomy for disabling Meniere disease. Ann Otolaryngol Chir Cervicofac 2005; 122: 271-80. ИНФОРМАЦИЯ ОБ АВТОРАХ / INFORMATION ABOUT THE AUTHORS
  71. De La Cruz A, Borne Teufert K, Berliner K. Transmastoid labyrinthectomy versus translabyrinthine vestibular nerve section: does cutting the vestibular nerve make a difference in outcome? Otol Neurotol 2007; 28: 801-8.
  72. Pullens B, Verschuur HP, van Benthem PP Surgery for Meniere’s disease. Cochrane Database Syst Rev 2013; 2: CD005395.
  73. Pang B, Costeloe A, Jackson NM, Babu S. Incidence of developing contralateral Meniere's disease in patients undergoing transmastoid labyrinthectomy for unilateral Meniere's disease. Ear Nose Throat J 2019; 2: 145561319854744.
  74. Diaz RC, LaRouere MJ, Bojrab DI. Quality-of-life assessment of Meniere's disease patients after surgical labyrinthectomy. Otol Neurotol 2007; 28 (1): 74-86.

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