CASE OF WERNIKE'S ENCEPHALOPATHY NON-ALCOHOLIC GENESIS: CLINICAL CASE

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Abstract

Wernike's encephalopathy (WE) is a difficult to recognize, but potentially curable disease with high doses of thiamine, related to urgent conditions. In the absence of specific treatment, or at a late start, WE turns into Korsakov syndrom (Wernike-Korsakov syndrom). Although WE most often develops in patients with alcoholism, many of WE cases have non-alcoholic genesis. We present the case of WE in a 46-year-old patient who denies alcohol abuse but has a history of food restriction with significant weight loss, which, apparently, was the cause of thiamine deficiency. Differential diagnosis was performed with stroke, stem encephalitis and Miller-Phisher syndrom. Despite the treatment, even after 4 months after discharge from the hospital, the patient still has atactic and mnestic disorders. The presented case demonstrates the difficulty of diagnosing WE in patients without a clear alcoholic history

About the authors

Anna V. Serdiuk

Pirogov Russian National Research Medical University

Email: aserdyuk@gmail.com
канд. мед. наук, ассистент каф. неврологии, нейрохирургии и медицинской генетики лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И. Пирогова» Москва, Россия

Elena A. Kovrazhkina

Federal Center for Cerebrovascular Disease and Stroke

ст. науч. сотр. ФГБУ ФЦППИ Москва, Россия

Natalia G. Abramova

City Clinical Hospital №31

врач-невролог отд-ния оказания помощи больным с инсультом ГБУЗ ГКБ №31 Москва, Россия

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