CASE OF WERNIKE'S ENCEPHALOPATHY NON-ALCOHOLIC GENESIS: CLINICAL CASE
- Authors: Serdiuk A.V.1, Kovrazhkina E.A.2, Abramova N.G.3
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Affiliations:
- Pirogov Russian National Research Medical University
- Federal Center for Cerebrovascular Disease and Stroke
- City Clinical Hospital №31
- Issue: Vol 21, No 9 (2019)
- Pages: 44-47
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/95193
- DOI: https://doi.org/10.26442/20751753.2019.9.190458
- ID: 95193
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Abstract
Wernike's encephalopathy (WE) is a difficult to recognize, but potentially curable disease with high doses of thiamine, related to urgent conditions. In the absence of specific treatment, or at a late start, WE turns into Korsakov syndrom (Wernike-Korsakov syndrom). Although WE most often develops in patients with alcoholism, many of WE cases have non-alcoholic genesis. We present the case of WE in a 46-year-old patient who denies alcohol abuse but has a history of food restriction with significant weight loss, which, apparently, was the cause of thiamine deficiency. Differential diagnosis was performed with stroke, stem encephalitis and Miller-Phisher syndrom. Despite the treatment, even after 4 months after discharge from the hospital, the patient still has atactic and mnestic disorders. The presented case demonstrates the difficulty of diagnosing WE in patients without a clear alcoholic history
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##article.viewOnOriginalSite##About the authors
Anna V. Serdiuk
Pirogov Russian National Research Medical University
Email: aserdyuk@gmail.com
канд. мед. наук, ассистент каф. неврологии, нейрохирургии и медицинской генетики лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И. Пирогова» Москва, Россия
Elena A. Kovrazhkina
Federal Center for Cerebrovascular Disease and Strokeст. науч. сотр. ФГБУ ФЦППИ Москва, Россия
Natalia G. Abramova
City Clinical Hospital №31врач-невролог отд-ния оказания помощи больным с инсультом ГБУЗ ГКБ №31 Москва, Россия