RECURRENT ISCHEMIC STROKE PREVENTION

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Abstract

Cardiovascular disorders are one of the primary mortality causes in Russia. Among them stroke has the second place after acute myocardial infarction. Only 16-13% of patients make a full recovery after ischemic stroke (IS) and return to their former way of life. In most of the patients disease results in disability or death. About 1/2 of IS of transient ischemic attack (TIA) survivors have a recurrent stroke in several days of weeks. A considerable number of recurrent strokes can be prevented with modern methods of secondary prevention. The article discusses tactics of risk factors control and antiplatelet therapy use in prevention of recurrent IS (RIS) based on American Heart Association (AHA) and American Stroke Association (ASA) guidelines with the focus on noncardioembolic stroke treatment. TIA and IS prevention is equally important and modern AHA/ASA guidelines are used in both. Alternatives of RIS prevention with the use of antiplatelet therapy (medications acetylsalicylic acid, clopidogrel, dipiridamol and their combinations); indications, adverse effects, effectiveness and safety, therapeutic dosages are described according to evidence based medicine data.

About the authors

ANNA A. PILIPOVICH

Sechenov First Moscow State Medical University (Sechenov University)

Email: aapilipovich@mail.ru
Cand. Sci. (Med.), Sechenov First Moscow State Medical University (Sechenov University) Москва, Россия

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