Mucosal permeability disturbances as a pathogenesis factor of gastrointestinal tract functional disorders: rationale and correction possibilities

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Abstract

The article presents modern view on mucosal epithelial barrier structure and its permeability. Interrelation of gastrointestinal tract dysfunction and tight junctions’ structural damage is discussed. Diagnostic possibilities of epithelium permeability and barrier function study in everyday practice and clinical studies are analyzed. Contribution of permeability disturbances in pathogenesis of different gastrointestinal tract functional disorders is discussed

About the authors

S. S Vialov

GMS Clinic

Email: svialov@mail.ru
канд. мед. наук, врач-гастроэнтеролог, гепатолог 121099, Russian Federation, Moscow, 1-i Nikoloshchepovskii per., d. 6, str. 1

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