Nosological diagnosis in patients with venous thromboembolic events

Venous thromboembolic events (VTE) include deep and superficial vein thrombosis as well as pulmonary thromboembolism that contributes significantly to mortality and disability in developed countries. VTE are often found in therapeutic patients, patients with blastomatous diseases, cardiac failure and various acute and chronic inflammatory diseases. It is important to consider all risk factors but still identification of the underlying disease that led to thrombophilia and hemodynamic disorders is often the priority. As an example we present a case of vena saphena magna thrombophlebitis that was complicated by small pulmonary arteries thrombembolia. Among the disease characteristics were: progressive heart failure with diastolic function failure predominance while there were no obvious causative factors. The attempts to find an explanation of multiple lesions resulted in diagnosing amyloidosis in the patient. A focused search of the underlying condition resulted in myeloma diagnosis in spite of lack of many indicative clinical and laboratory manifestations.

venous thromboembolic complications, pulmonary artery thrombembolia, myeloma