Autoimmune thyrotoxicosis syndrome (clinical case and literature review)

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Abstract

Thyrotoxicosis syndrome may have different ethiopathogenesis. Differential diagnosis of immune and non-immune thyrotoxicosis forms is crucial for treatment tactics development. The article describes a clinical case of female patient with Graves disease characterized with thyrotropic hormone receptor antibodies variability, who went into sustained remission against the background of conservative therapy with thyrostatics. The clinical impression is complemented with literature review that summarizes data on mechanisms that underlie thyroid gland autoimmune disease development or activate it.

About the authors

M. V Altashina

National Medical Research Center of the Endocrinology of the Ministry of Health of the Russian Federation

канд. мед. наук, науч. сотр. отд-ния вспомогательных репродуктивных технологий 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

E. A Panfilova

National Medical Research Center of the Endocrinology of the Ministry of Health of the Russian Federation

врач отд. терапевтической эндокринологии 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

M. A Terekhova

I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

студентка лечебного фак-та 119991, Russian Federation, Moscow, ul. Trubetskaia d. 8, str. 1*troshina@inbox.ru

E. A Troshina

National Medical Research Center of the Endocrinology of the Ministry of Health of the Russian Federation

чл.-кор. РАН, д-р мед. наук, проф., зав. отд. терапевтической эндокринологии 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

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