A clinical case of multiple amiodarone side effects development

The aim of the study was to present a clinical case of multiple amiodarone side effects development in a female patient after a long-term uncontrolled medication use and to demonstrate the case management. Special aspects of the clinical case. The patient was uncontrollably using amiodarone for 6 years in the total dose about 1500 g as she feared atrial fibrillation paroxysms development. After 2 years of treatment bradicardia and grey and purple skin tone developed, the patient concealed it with make-up, in 1 more year hand tremor appeared. In the next 2 years dry cough and dyspnea developed that forced the patient to seek medical advice. After medical assessment “amiodarone lung” was diagnosed, amoidarone withdrawal and a visit to cardiologist were recommended, but the patient persisted in amoidarone use. Cough and dyspnea intensified, dyspeptic, neurologic, and vision disorders developed. The patient sought medical assistance only when she became non-ambulant. After amoidarone withdrawal regression of most of the side effects was observed. Amoidarone withdrawal was possible only after alternative anti-arrhythmic therapy was adjusted. Conclusion. To avoid cases of multiple drug side effects development a complex approach to patients and the Ministry of Health of the Russian Federation warrant №403n from 11.07.2017 “On the approval of medication dispending order...” implementation are required

side effects, amoidarone, treatment