Statins and diabetes mellitus: cardiologist’s point of view

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Abstract

The article concerns statin use in patients with diabetes mellitus for cardiovascular risk reduction in primary and secondary prevention. Data on target levels of low-density lipoprotein in various subgroups of patients with diabetes mellitus receiving therapy with statins is presented. Also results of randomized clinical trials and meta-analyses that indicate the increase of risk for new events of diabetes mellitus associated with statins use are discussed. The article also presents data on the prevalence of this adverse event, its dependence on the dosage and duration of statin use, and benefit-risk profile. The populations of patients with the highest risk for diabetes mellitus associated with statins use are listed.

About the authors

O. D Ostroumova

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation; I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: ostroumova.olga@mail.ru
д-р мед. наук, проф. каф. факультетской терапии и профболезней, проф. каф. клин. фармакологии и пропедевтики внутренних болезней 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

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