Comparative efficacy of different antihistamines II generation in adult patients with seasonal allergic rhinitis

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Abstract

Allergic rhinitis plays leading role in the structure of allergic diseases. The second generation of antihistamines are frequently used to cure allergic rhinitis, including seasonal manifestations. In the following paper the comparative results of open, randomize clinical studies of efficiency, safety and influenceon quality of life of patients, suffered from seasonal allergic rhinitis, treated by original AGP II ebastine and generic AGP II cetirizine and loratadine are discussed. Its efficiency and safety providing control on mild nasal and non-nasal symptoms of seasonal rhinitis in mature patients have been demonstrated. It is noticed that the rate of onset of effect and its expression in relation to nasaland non-nasal symptoms were much efficient in patients, obtained ebastine 20 mg comparing with cetirizine 10 mg and loratadine 10 mg.

About the authors

O. S Bodnya

Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation

Email: os.bodnya@yandex.ru
канд. мед. наук, каф. клинической аллергологии ФГБОУ ДПО РМАНПО 125993, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1

N. M Nenasheva

Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation

д-р мед. наук, каф. клинической аллергологии ФГБОУ ДПО РМАНПО 125993, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1

G. V Andrenova

Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation

каф. клинической аллергологии ФГБОУ ДПО РМАНПО 125993, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1

D. O Sinyavkin

City Clinical Hospital of the Department of Health of Moscow №52

зав. клинико-диагностической лаб. №1 ГБУЗ ГКБ №52 123182, Russian Federation, Moscow, ul. Pekhotnaia, d. 3

Ya. V Bodnya

M.V.Lomonosov Moscow State University

аспирант, каф. математической статистики ФГБОУ ВО «МГУ им. М.В.Ломоносова» 119192, Russian Federation, Moscow, Lomonosovskii pr., d. 31, korp. 5

E. T Kubanova

M.V.Lomonosov Moscow State University

магистрант, фак-т экономики ФГБОУ ВО «МГУ им. М.В.Ломоносова» 119192, Russian Federation, Moscow, Lomonosovskii pr., d. 31, korp. 5

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