Bladder capacity and detrusor fibrosis as factors predicting the clinical course of the painful bladder/interstitial cystitis syndrome

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Abstract

Painful bladder syndrome / interstitial cystitis is a progressive disease of the bladder, leading to loss of its capacity and severe pelvic pain. Etiology remains unclear, one of the reasons is the violation of the integrity and permeability of the glycosaminoglycan layer of the urothelium due to circulatory disorders. Treatment remains empirical and multidomain. In connection with the development of detrusor fibrosis in complex therapy in the early stages of the disease should include drugs with antifibrotic action, for example, Longidaze.

About the authors

A. V Zaytsev

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: nauch.ot@mail.ru
д-р мед. наук, проф. каф. урологии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

O. A Tsybulya

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

канд. мед. наук, ст. лаборант каф. урологии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

M. V Kovylina

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

канд. мед. наук, рук. лаб. уроморфологии каф. урологии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

A. A Ibragimov

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

канд. мед. наук, аспирант каф. урологии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

D. Yu Pushkar

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

чл.-кор. РАН, д-р мед. наук, проф., зав. каф. урологии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова», главный уролог Минздрава России 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

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