Resistant vs uncontrolled arterial hypertension: management

Cover Page

Cite item

Abstract

In a review article presents an analysis of the main causes of resistance to antihypertensive treatment and uncontrolled arterial hypertension. The article deals with the discussion of the selection of combined antihypertensive treatment. The authors have shown the benefits of 3-component combined therapy consisting of calcium antagonist - amlodipine, angiotensin-converting enzyme inhibitor - perindopril and thiazide-like diuretic - indapamide. The analysis of the study demonstrates the efficacy and safety of fixed dose combination of perindopril/indapamide/amlodipine.

About the authors

T. V Adasheva

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: adashtv@mail.ru
д-р мед. наук, проф. каф. поликлинической терапии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

V. S Zadionchenko

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

д-р мед. наук, проф. каф. поликлинической терапии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

I. V Fedorova

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

канд. мед. наук, ассистент каф. поликлинической терапии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

N. B Shakhrai

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

канд. мед. наук, ассистент кафедры поликлинической терапии ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

References

  1. Mancia G, Fagard R, Narkiewicz K et al. ESH-ESC Task Force on the Management of Arterial Hypertension. 2013 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension. J Hypertens 2013; 31 (7): 1281-357.
  2. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertension 2009; 27: 2121-58.
  3. The Task Force for the management of arterial hypertension of the European Society of Hypertension and of the European Society of Cardiology. 2007 Guidelines for the management of arterial hypertension. J Hypertens 2007; 25: 1105-87.
  4. Чазова И.Е. и др. Распространенность факторов риска сердечно - сосудистых заболеваний в российской популяции больных артериальной гипертонией. Кардиология. 2014; 10: 4-12.
  5. Оганов Р.Г. и др. Эпидемиология артериальной гипертонии в России. Результаты федерального мониторинга 2003-2010 гг. Кардиоваск. терапия и профилактика. 2011; 10 (1): 9-13.
  6. Chow C.K, Teo K.K, Rangarajan S et al. PURE (Prospective Urban Rural Epidemiology) Study investigators. Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high -, middle -, and low - income countries. JAMA 2013; 310 (9): 959-68.
  7. Frohlich E.D. Classification of resistant hypertension. Hypertension 1988; 11: 1167-70.
  8. Mazzaglia G, Mantovani L.G, Sturkenboom M.C et al. Pattern of persistence with antihypertensive medication in newly diagnosed hypertensive patients in Italy: a retrospective cohort study in primary care. J Hypertens 2005; 23: 2093-100.
  9. Garg J.P, Elliot W.J, Folker A et al. RUSH University Hypertension Service. Resistant hypertension revisited: a comparison of two university - based cohorts. Am J Hypertens 2005; 18 (5): 619-26.
  10. Osterberg L, Blaschke T. Adherence to Medication. N Engl J Med 2005; 353: 487-97.
  11. Thoenes M, Neuberger H-R, Volpe M et al. Antihypertensive drug therapy and blood pressure control in men and women: an international perspective. J Hum Hypertens 2010; 24: 336-44.
  12. Gupta A.K, Arshad S, Poulter N.R. Compliance, safety, and effectiveness of fixed - dose combinations of antihypertensive agents, a meta - analysis. Hypertension 2010; 55: 399-407.
  13. Johnoston C.I, Fabris B, Yamada T. Comparative studies of tissue inhibition by angiotensin converting enzyme inhibitors. J Hypertension Suppl 1989; 7 (5): S11-7.
  14. Paul M, Mehr A.P, Kreutz R. Physiology of local renin - angiotensin systems. Physiol Rev 2006; 86: 747-803.
  15. Ceconi C, Fox K.M, Remme W.J et al. ACE inhibition with perindopril and endothelial dysfunction: results of a substudy of the EUROPA study PERTINENT. Cardiovasc Res 2007; 73: 237-46.
  16. Rodriguez-Granillo G.A. Long - term effect of Perindopril on coronary atherosclerosis progression [from the PERindopril’s Prospective Effect on Coronary aTherosclerosis by Angiography and Intra Vascular Ultrasound Evaluation (PERSPECTIVE) Study]. Am J Cardiol 2007; 100: 159-63.
  17. Pruss T, Wolf P.S. Preclinical studies of indapamide, a new 2methylindoline antihypertensive diuretic. Am Heart J 1983; 106 (1, Pt 2): 208-11.
  18. Gosse P, Sheridan D.J, Zannad F et al. Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1,5 mg versus enalapril 20 mg: the LIVE study. J Hypertens 2000; 18: 1465-75.
  19. Marre M, Puig J.G, Kokot F еt al. Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR study.J Hypertens 2004; 22: 1613-22.
  20. Асташкин Е.И., Глезер М.Г., Петров Е.А. Влияние индапамида на уровень радикалов кислорода, продуцируемых фагоцитами крови пациентов с сердечной недостаточностью. Рос. кардиол. журн. 2012; 4: 43-7.
  21. Hernaґndez R.H, Armas-Hernaґndez M.J, Zafar H.I, Armas-Padilla M.C. Calcium antagonists and atherosclerosis protection in hypertension. Am J Ther 2003; 10 (6): 409-14.
  22. Mason R.P, Rhodes D.G, Herbette L.G. Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes. J Med Chem 1991; 34 (3): 869-77.
  23. Phillips J.E, Mason R.P. Inhibition of oxidized LDL aggregation with a charged calcium antagonist amlodipine: role of electrostatic interactions. Atherosclerosis 2003; 168 (2): 239-44.
  24. BHS-NICE. Guidelines. Clinical management of primary hypertension in adults 2011. Updated April 2016. http://www.nice.org.uk
  25. Toth K. PIANIST Investigators. Antihypertensive efficacy of triple combination plus amlodipine in risk hypertensive patients. Am J Cardiovasc Drugs 2014; 14 (2): 137-45.
  26. Páll D, SzántóI, Szabó Z. Triple combination therapy in hypertension: the antihypertensive efficacy of treatment with perindopril, amlodipine, and indapamide SR. Clin Drug Investig 2014; 34: 701-8.
  27. Efficiency of the combined treatment of arterial hypertension in Ukraine: results of the TRIUMF multicenter study M.I.Lutay, on behalf of the TRIUMF multicenter study group. Український кардіол. журн. 2016; 4: 17-28.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2017 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).