Therapy for chronic heart failure: the possibilities of eplerenone

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Abstract

The development of chronic heart failure (CHF) is directly associated with a high risk of adverse outcomes in patients, including such case as sudden cardiac death. Medication management in CHF is a major health and social problem. The article deals with the use of mineralocorticoid receptor antagonists (MRA) in patients with CHF. The selective MRA - eplerenone plays the main role in this treatment, because of statistically significant evidence-based data.

About the authors

A. L Vertkin

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: kafedrakf@mail.ru
д-р мед. наук, проф., зав. каф. терапии, клинической фармакологии и скорой медицинской помощи ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

A. U Abdullaeva

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: kafedrakf@mail.ru
ассистент каф. терапии, клинической фармакологии и скорой медицинской помощи ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

G. Yu Knorring

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: knorring@mail.ru
канд. мед. наук, доц. каф. терапии, клинической фармакологии и скорой медицинской помощи ФГБОУ ВО «МГМСУ им. А.И.Евдокимова» 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

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