Blood pressure indices and sleep quality in elderly patients with chronic cerebral ischemia and arterial hypertension on the background of treatment with Pantocalcin (gopanthenic acid). The results of the PLATON noninterventional observational program

Purpose of the study - a study of the efficacy and safety of Pantocalcin (gopanthenic acid) in elderly patients with chronic cerebral ischemia on the background of arterial hypertension I-II stage. Material and methods. In an open, non-comparative non-interventional study, 862 patients aged 65 to 75 years (mean 69.07±2.97 years, 608 to 70.5% women) were treated with Pantocalcin 1500 mg/day for 3 months. Sleep quality indicators (Lida questionnaire), blood pressure (BP) level were monitored and evaluated, as well as a neuropsychological examination of the state of cognitive functions, which included testing using scales and tests (Brief scale of assessment of mental status, battery of tests for assessing frontal dysfunction, test drawing hours) and the subjective evaluation of the effectiveness of therapy was determined (according to the Scale of General Clinical Impression and Improvement of the State). Results and discussion. There was a violation of sleep quality in patients with inadequate control of blood pressure. Course appointment of 1500 mg/day dose of Pantocalcin contributed to improving the quality of night sleep and improve cognitive function. In patients with initially elevated blood pressure, following recommendations of the main antihypertensive therapy and taking Pantocalcin in doses of 1500 mg/day, the systolic and diastolic BP values were reduced to the target values. The conclusion. The use of Pantocalcin in patients with chronic cerebral ischemia and hypertension increases the quality of BP control, positively affects the state of cognitive functions, is effective and safe.

arterial hypertension, chronic cerebral ischemia, Pantocalcin, treatment