Differences in the effectiveness of treatment of cholelithiasis and biliary sludge with various drugs of ursodeoxycholic acid
- Authors: Vyalov S.S1,2
-
Affiliations:
- People’s Friendship University of Russia
- N.E.Bauman Moscow State Technical University
- Issue: Vol 19, No 8-2 (2017)
- Pages: 64-68
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/94650
- DOI: https://doi.org/10.26442/2075-1753_19.8.2.64-68
- ID: 94650
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Abstract
Purpose: comparative analysis of clinical efficacy of ursodeoxycholic acid drugs for treatment of cholelithiasis and biliary sludge. Materials and methods. A retrospective multicenter study of 5 thousand patients was conducted, in which the actual occurrence of various stages of cholelithiasis in clinical practice was assessed. The effectiveness of treatment of cholelithiasis and biliary sludge in 210 patients receiving ursodeoxycholic acid therapy was evaluated. Results. Analysis of the patients structure on an outpatient visit revealed a frequency of cholelithiasis morbidity 15.5%. The prevalence of mild forms of cholelithiasis was 9.3%. The greatest effectiveness of reducing the size of gallstones and biliary sludge symptoms according to the results of the study was noted in the group whose participants took Ursosan. Conclusion. Сhoosing a treatment it is necessary to take into account the peculiarities of ursodeoxycholic acid preparations, the quality of production and substance. Ursosan may be a drug of choice for therapy of cholelithiasis.
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##article.viewOnOriginalSite##About the authors
S. S Vyalov
People’s Friendship University of Russia; N.E.Bauman Moscow State Technical University
Email: svialov@mail.ru
канд. мед. наук, доц. каф. общей практики, врач-гастроэнтеролог, гепатолог GMS clinic & hospitals. 117198, Russian Federation, Moscow, ul. Miklukho-Maklaya, d. 6
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