Autonomic heart neuropathy and its correction in type 2 diabetic patients

Diabetic autonomic neuropathy of the heart develops during 3-5 years of diabetes, leads to myocardial contractility decreasing, causes cardiac arrhythmia and increases the incidence of latent ischemia and myocardial infarction. The aim of this study was to determine the effect of Cocarnit in heart autonomic neuropathy symptoms in patients with diabetes. Material and methods. The study involved 50 patients with type 2 diabetes. All patients received Cocarnit (lyophilisates for solution for intramuscular injection, administered one time per day intramuscularly at a dose of 2 ml per day for 9 days, then 3 more injections of 2 ml every other day). The main criteria for the effectiveness of the study was the dynamics of the symptoms on 5 standard tests D.Ewing and changes in heart rate variability parameters. Results and conclusions. Application of Cocarnit safe, no side effects, and improves the overall clinical impression of the patients on a scale of GCIC. Its use has a beneficial effect on the cardio-vascular autonomic nervous system, which manifests in improving the results of tests D. Ewing. Cocarnit therapy increases heart rate variability, which manifests an increase in its temporal and spectral parameters according to Holter monitoring. Cocarnit intramuscular injection once a day at a dose of 2 ml per day for 9 days, then 3 more injections of 2 ml every other day can be recommended to patients for treatment of the manifestations of heart.diabetic autonomic neuropathy.

diabetes mellitus, heart, neuropathy