Macronodular bilateral adrenal hyperplasia: diagnose the aberrant receptors and current aspects of treatment

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Abstract

The investigation strategy for identification the specific expression of aberrant receptors includes ligand-induced tests. The identification of aberrant receptors provides an opportunity for new pharmacological therapeutic strategies. However, the specific aberrant receptors antagonists administration is limited due to the insufficient data on the effectiveness of medication, and side effects of drugs. Currently there is no unified approach of the management of patients with MBAH. Thus, researches, including genomic, directed at improvement of timely diagnostics of disease and development of new therapeutic and potentially preventive measures against MBAH, are topical.

About the authors

M. Yu Yukina

Endocrinology Research Center of the Ministry of Health of the Russian Federation

Email: kuronova@yandex.ru
канд. мед. наук, врач первой категории, ст. науч. сотр. отд-ния терапии с группой ожирения ФГБУ ЭНЦ 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

N. F Nuralieva

Endocrinology Research Center of the Ministry of Health of the Russian Federation

Email: Nnurana@yandex.ru
клин. ординатор ФГБУ ЭНЦ 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

D. G Beltsevich

Endocrinology Research Center of the Ministry of Health of the Russian Federation

Email: belts67@gmail.com
д-р мед. наук, глав. науч. сотр. отд-ния хирургии ФГБУ ЭНЦ 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

E. A Troshina

Endocrinology Research Center of the Ministry of Health of the Russian Federation

Email: troshina@inbox.ru
д-р мед. наук, проф., зав. отд-нием терапии с группой ожирения ФГБУ ЭНЦ 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

N. M Platonova

Endocrinology Research Center of the Ministry of Health of the Russian Federation

Email: doc-platonova@inbox.ru
д-р мед. наук, врач высшей категории, глав. науч. сотр. отд-ния терапии с группой ожирения ФГБУ ЭНЦ 117036, Russian Federation, Moscow, ul. Dmitria Ul'ianova, d. 11

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