Cognitive impairments in some deficit and dismetabolic states

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Abstract

Cognitive impairments (CI) as one of the symptoms of the nervous system are often found in various states of deficit and dismetabolism. There is good evidence that CI is one of the main manifestations of developing encephalopathy in chronic liver disease, kidney disease, diabetes. At deficiency of cyanocobalamin (vitamin B12) and folic acid, hyperhomocysteinemia is observed in cognitive decline up to the development of dementia. The features of the CI in alcoholic lesion of the central nervous system are also discussed. The possible mechanisms of neuronal damage in the brain and dismetabolic of deficit states. The results of randomized clinical studies examining the efficacy of vitamins in patients with CI. Special attention is given to Berocca vitamins and minerals.

About the authors

N. V Pizova

Yaroslavl State Medical University of the Ministry of Health of the Russian Federation

Email: pizova@yandeх.ru
д-р мед. наук, проф. каф. неврологии и медицинской генетики с курсом нейрохирургии ГБОУ ВПО ЯГМУ 150000, Russian Federation, Yaroslavl, ul. Revoliutsionnaia, d. 5

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