Non-hormonal correction of vasomotor symptoms in peri - and postmenopausal women

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Abstract

Frequency of climacteric symptoms in menopausal reaches 40-60%. One of the main reasons of neurovegetative reactions that develop during menopause, is a change in the functional state of hypothalamic centers and violation of neurotransmitter secretion. A prospective study including 30 patients with autonomic manifestations of climacteric syndrome was held. Within 3 months of therapy based on melatonin (Melaxen) in a daily dose of 3 mg was used. Dynamics of psycho-emotional state of self-assessed by a specialized scales: Spielberger-Khanin, A.M.Wayne questionnaire and modified menopausal index by Cooperman. Hormonal study was carried out before treatment and at 3 months. Subjective assessment of the quality of life and the level of anxiety in patients allow them to carry a high risk of developing the syndrome of autonomic dysfunction. Against the background of the 3-month course of the use of melatonin showed improvement of quality of life of patients.

About the authors

S. A Levakov

I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

д-р мед. наук, проф., зав. каф. акушерства и гинекологии ИПО ГБОУ ВПО Первый МГМУ им. И.М.Сеченова 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2

E. I Borovkova

I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: katyanikitina@mail.ru
д-р мед. наук, проф. каф. акушерства и гинекологии ИПО ГБОУ ВПО Первый МГМУ им. И.М.Сеченова 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2

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