Experience of ivabradine application in patients with comorbid pathology

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Abstract

The aim of the study is to assess the antiarrhythmic action of ivabradine in patients with comorbid pathology, and associated with the combination of effort angina and chronic obstructive pulmonary disease following coronary artery bypass graft surgery.Materials and methods: we examined 120 men with stable effort angina functional classes II-III 3 years after coronary artery bypass graft surgery using the hardware-software complexes “ETON” and “Holter-DMS”. The article describes the following results: the application of ivabradine can reduce ventricular extrasystoles.Conclusion: we recommend using ivabradine in patients with ischemic heart disease combined with chronic obstructive pulmonary disease after coronary artery bypass graft surgery because of significant antianginal effect of this drug: such as reducing the number of angina attacks, improving the quality of life of patients, increasing heart rate variability.

About the authors

I. V Kochetkova

N.N.Burdenko Voronezh State Medical University of the Ministry of Health of the Russian Federation

Email: iri4217@yandex.ru
канд. мед. наук, ассистент каф. госпитальной терапии и эндокринологии ГБОУ ВПО ВГМУ им. Н.Н.Бурденко 394036, Russian Federation, Voronezh, ul. Studen- cheskaia, d. 10

T. M Chernykh

N.N.Burdenko Voronezh State Medical University of the Ministry of Health of the Russian Federation

д-р мед. наук, зав. каф. госпитальной терапии и эндокринологии ГБОУ ВПО ВГМУ им. Н.Н.Бурденко 394036, Russian Federation, Voronezh, ul. Studen- cheskaia, d. 10

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