Several cases of ticagrelor application on conducting fibrinolytic therapy of ST elevation myocardial infarction

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Abstract

There have been found limited number of publications devoted to ticagrelor application as a part of antiplatelet treatment on conducting systemic thrombolysis in patients with ST elevation myocardial infarction. The paper showed the analysis of such therapy safety, based on hospital data registers; we found out 54 cases of ticagrelor application within the first 24 hours after thrombolysis. The usage of ticagrelor was not accompanied by an increased risk of bleeding complications in comparison with standard clopidogrel therapy.

About the authors

I. G Pochinka

Nizhny Novgorod State Medical Academy of the Ministry of Health of the Russian Federation; City Clinical Hospital №13

Email: pochinka4@ya.ru
доц. ГБОУ ВПО НГМА, зав. отд-нием ГБУЗ НО ГКБ №13 603005, Russian Federation, Nizhny Novgorod, pl. Minina I Pozharskogo, d. 10/1

S. N Botova

Nizhny Novgorod State Medical Academy of the Ministry of Health of the Russian Federation; City Clinical Hospital №13

ассистент ГБОУ ВПО НГМА, зав. отд-нием ГБУЗ НО ГКБ №13 603005, Russian Federation, Nizhny Novgorod, pl. Minina I Pozharskogo, d. 10/1

L. G Strongin

Nizhny Novgorod State Medical Academy of the Ministry of Health of the Russian Federation

проф., зав. каф. ГБОУ ВПО НГМА 603005, Russian Federation, Nizhny Novgorod, pl. Minina I Pozharskogo, d. 10/1

A. V Suvorov

City Clinical Hospital №39

зав. отд-нием ГБУЗ НО ГКБ №39 603950, Russian Federation, Nizhny Novgorod, Moskovskoe sh., d. 144

K. I D'iachkova

City Clinical Hospital №13

врач ГБУЗ НО ГКБ №13 603018, Russian Federation, Nizhny Novgorod, ul. Patriotov, d. 51

M. S Pimankina

Nizhny Novgorod State Medical Academy of the Ministry of Health of the Russian Federation

ассистент ГБОУ ВПО НГМА 603005, Russian Federation, Nizhny Novgorod, pl. Minina I Pozharskogo, d. 10/1

References

  1. Wallentin L, Becker R.C, Budaj A et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009; 361: 1045-57.
  2. Steg G, James S.K, Atar D et al. ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2012; 33: 2569-619.
  3. Goudevenos J, Ntalas I, Xanthopoulou I et al. Use of ticagrelor in patients with ST-elevation myocardial infarction undergoing thrombolysis. J Thromb Thrombolysis 2014; 37: 356-7.

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