Risk of hypertension development in patientswith oncological diseases under anticancer treatment

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Abstract

In recent years, a new direction in medicine has been formed, combining the efforts of cardiologists and oncologists - cardio-oncology, whose objectives are to develop and optimize the algorithms of collaborative management of cancer patients, to minimize cardiotoxic effects of antineoplastic treatment that would improve prognosis and prolong their life. It is known that chemotherapeutic drugs have cardio - and vasotoxication effects, contributing to the development and aggravation of existing cardiovascular disease. Arterial hypertension (AH) is one of the complications of antineoplastic therapy of malignant oncological diseases and most often occurs in the prescription of inhibitors of the receptor of epidermal growth factor. The true prevalence of "new-onset" hypertension in these patients can hardly be defined, and it varies considerably depending on the type, dose, time-period of chemotherapy. Examination and treatment of patients with oncological diseases, who developed AH due to chemotherapy, are conducted according to recommendations; however, there are peculiarities in prescription of different antihypertensive drugs.

About the authors

I. E Chazova

Russian Cardiological Scientific-Industrial Complex of the Ministry of Health of the Russian Federation

чл.-кор. РАН, д-р мед. наук, проф., и.о. ген. дир. ФГБУ РКНПК, дир. ИКК им. А.Л.Мясникова ФГБУ РКНПК 121552, Russian Federation, Moscow, ul. 3-ia Che- repkovskaia, d. 15a

E. V Oshchepkova

Russian Cardiological Scientific-Industrial Complex of the Ministry of Health of the Russian Federation

д-р мед. наук, проф., рук. отд. регистров сердечно-сосудистых заболеваний и отд. координации и мониторинга науч. программ ФГБУ РКНПК 121552, Russian Federation, Moscow, ul. 3-ia Che- repkovskaia, d. 15a

M. Yu Kirillova

Russian Cardiological Scientific-Industrial Complex of the Ministry of Health of the Russian Federation

Email: register.ihd.rus@gmail.com
канд. мед. наук, мл. науч. сотр. отд. регистров сердечно-сосудистых заболеваний ФГБУ РКНПК 121552, Russian Federation, Moscow, ul. 3-ia Che- repkovskaia, d. 15a

M. B Stenina

N.N.Blokhin Russian Cancer Research Center of the Ministry of Health of the Russian Federation

д-р мед. наук, вед. науч. сотр. отд-ния клин. фармакологии и химиотерапии ФГБУ РОНЦ им. Н.Н.Блохина 115478, Russian Federation, Moscow, Kashirskoe sh., d. 23

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