Lechenie erektil'noy disfunktsii: effekty sildenafila
- Authors: Vertkin A.L1, Morgunov L.Y.1
-
Affiliations:
- ГБОУ ВПО МГМСУ им. А.И.Евдокимова Минздрава России
- Issue: Vol 16, No 2 (2014)
- Pages: 63-66
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/94047
- ID: 94047
Cite item
Full Text
Abstract
Исследования в области нейрофизиологии эрекции привели к существенному прогрессу в лечении больных с эректильной дисфункцией ЭД. Они увенчались созданием принципиально нового средства в лечении данного заболевания - ингибитора фосфодиэстеразы 5-го типа (ФДЭ-5) силденафила, отвечающего всем современным требованиям, предъявляемым к терапии ЭД. Этот препарат признан средством 1-й линии в лечении ЭД, он высокоэффективен и надежен, прост в употреблении, обладает малым числом побочных эффектов. На сегодня силденафил является «золотым стандартом» в лечении ЭД.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
A. L Vertkin
ГБОУ ВПО МГМСУ им. А.И.Евдокимова Минздрава России
L. Yu Morgunov
ГБОУ ВПО МГМСУ им. А.И.Евдокимова Минздрава России
References
- Ayta I.A, Mc Kinlay J.B, Krane R.J. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int 1999; 84 (1): 50-6.
- Wagner G, Fugl-Meyer K.S, Fugl-Meyer A.R. Impact of erectile dysfunction on quality of life: patient and partner perspectives. Int J Impot Res 2000; 4 (S1): 44-6.
- Corona G, Mondaini N, Ungar A et al. Phosphodiesterase type 5 (PDE5) inhibitors in erectile dysfunction: the proper drug for the proper patient. J Sex Med 2011; 8 (12): 3418-32.
- Gresser U, Gleiter C.H. Erectile dysfunction: comparison of efficacy and side effects of the PDE-5 inhibitors sildenafil, vardenafil, and tadalafil review of the literature. Eur J Med Res 2002; 7: 435-46.
- Mc Cullough A.R. Four - year review of sildenafil citrate. Rev Urol 2002; 4 (Suppl. 3): S26-38.
- Carson C.C. Sildenafil: a 4-yearupdate in the treatment of 20 million erectile dysfunction patients. Curr Urol Rep 2003; 4 (6): 488-96.
- Brown M, Prisant L.M, Collins M. Effect of sildenafil in patients with erectile dysfunction takin antihypertensive therapy. Am J Hematol 2001; 14: 70-3.
- Sunwoo S, Kim Y.S, Cho B.L et al. Post - marketing surveillance study of the safety and efficacy of sildenafil prescribed in primary care to erectile dysfunction patients. Int J Impot Res. 2005; 17 (1): 71-5.
- Rashid A. The efficacy and safety of PDE5 inhibitors. Clin Cornerstone 2005; 7 (1): 47-56.
- Taylor J et al. Differences in side - effect duration and related bother levels between phosphodiesterase type 5 inhibitors. BJU Int 2009; 103: 1392-5.
- Leslie S.J et al. No adverse hemodynamic interaction between sildenafil and red wine. Clin Pharmacol Ther 2004; 76: 365-70.
- Kennedy S.H, Dugre H, Defoy I. A multicenter, double - blind, placebo - controlled study of sildenafil citrate in Canadian men with erectile dysfunction and untreated symptoms of depression, in the absence of major depressive disorder. Int Clin Psychopharmacol 2011; 26 (3): 151-8.
- Dording C.M, La Rocca R.A, Hails K.A et al. The effect of sildenafil on quality of life. Ann Clin Psychiatry 2013; 25 (1): 3-10.
- Abolyosr A, Elsagheer G.A, Abdel-Kader M.S et al. Evaluation of the effect of sildenafil and/or doxazosin on Benign prostatic hyperplasia - related lower urinary tract symptoms and erectile dysfunction. Urol Ann 2013; 5 (4): 237-40.
- Cui H, Liu B, Song Z et al. Efficacy and safety of long - term tadalafil 5 mg once daily combined with sildenafil 50 mg as needed at the early stage of treatment for patients with erectile dysfunction. Andrologia 2014 Jan 6; doi: 10.1111/and.12216.
- Spitzer M, Bhasin S, Travison T.G et al. Sildenafil increases serum testosterone levels by a direct action on the testes. Andrology 2013; 1 (6): 913-8.
- Buvat J, Hatzichristou D, Maggi M et al. Efficacy, tolerability and satisfaction with sildenafil citrate 100-mg titration compared with continued 50-mg dose treatment in men with erectile dysfunction. BJU Int 2008; 102 (11): 1645-50.
