Asthmatic status of a child with severe bronchial asthma. Case report
- Authors: Ilyenkova N.A.1,2, Sergienko D.F.3, Stepanova L.V.1, Pastukhova S.Y.4, Dobronovich L.M.4
-
Affiliations:
- Voyno-Yasenetsky Krasnoyarsk State Medical University
- Research Clinical Institute of Childhood
- Astrakhan State Medical University
- Berzon Krasnoyarsk Interdistrict Clinical Hospital №20
- Issue: Vol 27, No 9 (2025): Otorhinolaryngology and pulmonology
- Pages: 517-520
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/356627
- DOI: https://doi.org/10.26442/20751753.2025.9.203472
- ID: 356627
Cite item
Full Text
Abstract
The article describes a clinical case of asthmatic status in a child with severe bronchial asthma, which clearly demonstrates the importance of organizing rational medical care for this group of patients at the stage of a territorial polyclinic, where timely measures should be taken to assess the effectiveness of current anti-inflammatory therapy, review its scope, and especially paperwork to provide patients with vital medicines in the preferential drug treatment system provision of citizens. Personalized phenotype determination and therapy selection are needed for patients who do not achieve control on medium and high doses of inhaled glucocorticosteroids in combination with long-acting β2-agonists and who have a history of severe exacerbations. It is important to observe the continuity of medical care for such patients at the inpatient and outpatient stages.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
Natalya A. Ilyenkova
Voyno-Yasenetsky Krasnoyarsk State Medical University; Research Clinical Institute of Childhood
Email: ludok83@yandex.ru
ORCID iD: 0000-0001-8058-7806
D. Sci. (Med.), Prof.
Russian Federation, Krasnoyarsk; MoscowDiana F. Sergienko
Astrakhan State Medical University
Author for correspondence.
Email: ludok83@yandex.ru
ORCID iD: 0000-0002-0875-6780
D. Sci. (Med.)
Russian Federation, AstrakhanLudmila V. Stepanova
Voyno-Yasenetsky Krasnoyarsk State Medical University
Email: ludok83@yandex.ru
ORCID iD: 0000-0003-3241-7655
Cand. Sci. (Med.)
Russian Federation, KrasnoyarskSvetlana Y. Pastukhova
Berzon Krasnoyarsk Interdistrict Clinical Hospital №20
Email: ludok83@yandex.ru
ORCID iD: 0009-0009-5587-5940
Deputy Chief doctor
Russian Federation, KrasnoyarskLilya M. Dobronovich
Berzon Krasnoyarsk Interdistrict Clinical Hospital №20
Email: ludok83@yandex.ru
ORCID iD: 0009-0005-4116-3118
Pediatrician
Russian Federation, KrasnoyarskReferences
- Global Initiative for Asthma. Global strategy for asthma management and prevention. Updated 2024. Available at: www.ginaastma.org. Accessed: 20.01.2025.
- Колосова Н.Г., Денисова В.Д., Шаталина С.И. Контролирующая терапия бронхиальной астмы у детей – что нового? Медицинский Совет. 2024;(19):52-7 [Kolosova NG, Denisova VD, Shatalina SI. Management of childhood asthma: What is new? Medicinskiy Sovet. 2024;(19):52-7 (in Russian)]. doi: 10.21518/ms2024-416
- Айсанов З.Р., Курбачева О.М., Емельянов А.В., и др. Бремя заболевания и особенности ведения пациентов с тяжелой бронхиальной астмой в России: результаты международного наблюдательного исследования. Терапевтический архив. 2024;96(3):212-7 [Aisanov ZR, Kurbacheva OM, Emelyanov AV, et al. Burden and management of severe asthma in Russia: results from international observational study. Terapevticheskii Arkhiv (Ter. Arkh.). 2024;96(3):212-7 (in Russian)]. doi: 10.26442/00403660.2024.03.202625
- Farinha I, Heaney LG. Barriers to clinical remission in severe asthma. Respir Res. 2024;25(1):178. doi: 10.1186/s12931-024-02812-3
- Holguin F, Cardet JC, Chung KF, et al. Лечение тяжелой бронхиальной астмы: рекомендации Европейского респираторного общества и Американского торакального общества. Пульмонология. 2021;31(3):272-95 [Holguin F, Cardet JC, Chung KF, et al. Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline. Pulmonologiya. 2021;31(3):272-95 (in Russian)]. doi: 10.18093/0869-0189-2021-31-3-272-295
- Бронхиальная астма. Клинические рекомендации. Министерство здравоохранения РФ. M. 2024 [Bronkhialnaia astma. Klinicheskie rekomendacii. Ministerstvo zdravookhraneniia RF. Moscow. 2024 (in Russian)].
- Национальная программа «Бронхиальная астма у детей. Стратегия лечения и профилактика». 6-е изд., перераб. и доп. М.: МедКом-Про, 2021 [Natsionalnaia programma “Bronkhialnaia astma u detei. Strategiia lecheniia i profilaktika”. 6-e izd., pererab. i dop. Moscow: MedKom-Pro, 2021 (in Russian)].
- Авдеев С.Н., Линник С.А., Туменко Е.Е. Анализ лекарственного обеспечения пациентов с бронхообструктивными заболеваниями в Российской Федерации. Общественное здоровье. 2023;3(4):25-36 [Avdeev SN, Linnik SA, Tumenko EE. Analysis of drug provision for patients with broncho-obstructive diseases in the Russian Federation. Public Health. 2023;3(4):25-36 (in Russian)]. doi: 10.21045/2782-1676-2023-3-4-25-36
- Елисеева Е.В., Переломова О.В., Манеева Е.С., и др. Интегративная Шкала как инновационный инструмент повышения эффективности Программы обеспечения отдельных категорий граждан необходимыми лекарственными препаратами. Качественная клиническая практика. 2022;3:10-8 [Eliseeva EV, Perelomova OV, Maneeva ES et al. The Integrative Scale as an innovative method to increase the effectiveness of the Program for Providing Certain Categories of Citizens with Necessary Medicines. Good Clinical Practice. 2022;(3):10-8 (in Russian)]. doi: 10.37489/2588-0519-2022-3-10-18
- Bourdin A, Brusselle G, Couillard S et al. Phenotyping of Severe Asthma in the Era of Broad-Acting Anti-Asthma Biologics. J Allergy Clin Immunol Pract. 2024;12(4):809-23. doi: 10.1016/j.jaip.2024.01.023
- Pelaia C, Melhorn J, Hinks TS et al. Type 2 severe asthma: pathophysiology and treatment with biologics. Expert Rev Respir Med. 2024;18(7):485-98. doi: 10.1080/17476348.2024.2380072
- Нестеренко З.В., Белова А.А., Моисеенкова Ю.А., и др. Клинический случай тяжелого течения бронхиальной астмы у подростка. Медицина: теория и практика. 2022;7(3):30-4 [Nesterenko ZV, Belova AA, Moiseenkova YuA, et al. Clinical case of severe bronchial asthma at a teenager. Medicina: teoria i praktika. 2022;7(3):30-4 (in Russian)]. doi: 10.56871/4297.2022.20.60.005
- Приказ от 15.02.2017 г. №1071 Об утверждении порядка осуществления Фармаконадзора с изменениями от 16.07.2020 Федеральной службы по надзору в сфере здравоохранения РФ. Режим доступа: publication.pravo.gov.ru/document/view/0001201703210040. Ссылка активна на 06.02.2025 [Order No. 1071 of February 15, 2017, on approval of the procedure for implementing Pharmacovigilance, as amended on July 16, 2020, of the Federal Service for Surveillance in Healthcare of the Russian Federation. Available at: publication.pravo.gov.ru/document/view/0001201703210040. Accessed: 06.02.2025 (in Russian)].
- Mahesh S, Ramamurthy MB. Management of Acute Asthma in Children. Indian J Pediatr. 2022;89(4):366-72. doi: 10.1007/s12098-021-04051-6
Supplementary files

