Hyperuricemia and acute decompensation of heart failure: is there a causative link? A review
- Authors: Sarieva L.H.1, Nasonova S.N.1, Zhirov I.V.1,2, Zhirova I.A.3, Tereshchenko S.N.1
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Affiliations:
- Chazov National Medical Research Center of Cardiology
- Russian Medical Academy of Continuous Professional Education
- Patrice Lumumba People’s Friendship University of Russia
- Issue: Vol 26, No 1 (2024): Cardiology and Nephrology
- Pages: 26-30
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/256817
- DOI: https://doi.org/10.26442/20751753.2024.1.202591
- ID: 256817
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Abstract
The relevance and importance of the problem of acute decompensation of heart failure for the health care system not only in Russia, but also in the whole world is caused by a significant increase in the number of hospitalizations, associated increase in financial costs and extremely unfavorable prognosis in this group of patients. The article is devoted to the pathogenesis of acute decompensation of heart failure and the place of asymptomatic hyperuricemia in the development of this condition. Hyperuricemia is considered as a prognostic marker of unfavorable prognosis in patients with both cardiovascular diseases in general and acute decompensation of heart failure in particular. Special emphasis is made on approaches to drug therapy, tactics of xanthine oxidase inhibitor allopurinol use, doses are analyzed in terms of efficacy, influence on prognosis, methods of achieving and controlling target values of hyperuricemia are discussed.
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##article.viewOnOriginalSite##About the authors
Laura H. Sarieva
Chazov National Medical Research Center of Cardiology
Author for correspondence.
Email: laur.sarieva@yandex.ru
ORCID iD: 0000-0001-5865-1680
Graduate Student
Russian Federation, MoscowSvetlana N. Nasonova
Chazov National Medical Research Center of Cardiology
Email: dr.nasonova@mail.ru
ORCID iD: 0000-0002-0920-7417
Cand. Sci. (Med.)
Russian Federation, MoscowIgor V. Zhirov
Chazov National Medical Research Center of Cardiology; Russian Medical Academy of Continuous Professional Education
Email: izhirov@mail.ru
ORCID iD: 0000-0002-4066-2661
D. Sci. (Med.), Chazov National Medical Research Center of Cardiology, Russian Medical Academy of Continuous Professional Education
Russian Federation, Moscow; MoscowIrina A. Zhirova
Patrice Lumumba People’s Friendship University of Russia
Email: irinaili@mail.ru
ORCID iD: 0000-0002-6621-2052
Cand. Sci. (Med.)
Russian Federation, MoscowSergey N. Tereshchenko
Chazov National Medical Research Center of Cardiology
Email: laur.sarieva@yandex.ru
ORCID iD: 0000-0001-9234-6129
D. Sci. (Med.), Prof.
Russian Federation, MoscowReferences
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