Coagulopathy in cardiac surgery in the context of the COVID-19 pandemic: A review
- Authors: Basanets A.V.1, Rakhimov A.Z.1, Ibrahimov R.M.1, Asymbekova E.U.1, Tugeeva E.F.1, Buziashvili Y.I.1
-
Affiliations:
- Bakulev National Medical Research Center of Cardiovascular Surgery
- Issue: Vol 25, No 1 (2023): Cardiovascular diseases
- Pages: 58-62
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/131648
- DOI: https://doi.org/10.26442/20751753.2023.1.202175
- ID: 131648
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Abstract
Patients with concomitant cardiovascular diseases and traditional cardiovascular risk factors (age, male gender, arterial hypertension, diabetes mellitus and obesity) belong to a particularly vulnerable cohort characterized by progressive severe COVID-19 and high hospital mortality. Thorough screening strategies, standardized guidelines, and center-level protocols are needed to identify patients who are at greater risk of postoperative complications and mortality. Therefore, in this review, we consider the possible impact of COVID-19 on the patency of bypass vessels in the coronary arteries, mainly in relation to venous shunts. However, this hypothesis needs to be confirmed and further studied in the framework of clinical randomized trials.
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##article.viewOnOriginalSite##About the authors
Anna V. Basanets
Bakulev National Medical Research Center of Cardiovascular Surgery
Author for correspondence.
Email: anna.basanets1000@gmail.com
ORCID iD: 0000-0002-1093-9834
Resident
Russian Federation, MoscowAkmal Z. Rakhimov
Bakulev National Medical Research Center of Cardiovascular Surgery
Email: anna.basanets1000@gmail.com
ORCID iD: 0000-0002-9370-9419
Cand. Sci. (Med.)
Russian Federation, MoscowRustam M. Ibrahimov
Bakulev National Medical Research Center of Cardiovascular Surgery
Email: anna.basanets1000@gmail.com
ORCID iD: 0000-0003-4164-5051
Cand. Sci. (Med.)
Russian Federation, MoscowElmira U. Asymbekova
Bakulev National Medical Research Center of Cardiovascular Surgery
Email: anna.basanets1000@gmail.com
ORCID iD: 0000-0002-5422-2069
D. Sci. (Med.)
Russian Federation, MoscowElvina F. Tugeeva
Bakulev National Medical Research Center of Cardiovascular Surgery
Email: anna.basanets1000@gmail.com
ORCID iD: 0000-0003-1751-4924
D. Sci. (Med.)
Russian Federation, MoscowYuri I. Buziashvili
Bakulev National Medical Research Center of Cardiovascular Surgery
Email: anna.basanets1000@gmail.com
ORCID iD: 0000-0001-7016-7541
D. Sci. (Med.), Prof., Acad. RAS
Russian Federation, MoscowReferences
- Iba T, Levy JH, Connors JM. The unique characteristics of COVID-19 coagulopathy. Crit Care. 2020;24(1):360. doi: 10.1186/s13054-020-03077-0
- Самородов А.В., Золотухин К.Н. Профилактика COVID-19-ассоциированного нарушения гемостаза у пациента со стентированными коронарными артериями. Клинический случай. Креативная хирургия и онкология. 2020;10(2):137-42 [Samorodov AV, Zolotukhin KN. Prevention of COVID-19-associated Haemostasis Failure in Patient with Stented Coronary Arteries: a Clinical Case. Creative Surgery and Oncology. 2020;10(2):137-42 (in Russian)]. doi: 10.24060/2076-3093-2020-10-2-137-142
- Doglietto F, Vezzoli M, Gheza F. Factors Associated with Surgical Mortality and Complications Among Patients with and Without Coronavirus Disease 2019 (COVID-19) in Italy. JAMA Surg. 2020;155(8):1-14. doi: 10.1001/jamasurg.2020.2713
- Bansal M. Cardiovascular disease and COVID-19. Diabetes Metab Syndr. 2020;14(3):247-50. doi: 10.1016/j.dsx.2020.03.013
- Mehra M, Desai S, Kuy S, et al. Retraction: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med. 2020;382(26):2582. doi: 10.1056/NEJMc2021225
- Gavriilaki E, Anyfanti P, Gavriilaki M, et al. Endothelial Dysfunction in COVID-19: Lessons Learned from Coronaviruses. Curr Hypertens Rep. 2020;22(9):63. doi: 10.1007/s11906-020-01078-6
- Siddiqi H, Libby P, Ridker P. COVID-19 – A vascular disease. Trends Cardiovasc Med. 2021;31(1):1-5. doi: 10.1016/j.tcm.2020.10.005
- Pons S, Fodil S, Azoulay E, Zafrani L. The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection. Crit Care. 2020;24(1):353. doi: 10.1186/s13054-020-03062-7
- Pourafkari L, Mirza-Aghzadeh-Attari M, Zarrintan A, Mousavi-Aghdas SA. Clinical Experience, Pathophysiology, and Considerations in the Prophylaxis and Treatment of Hypercoagulopathy of COVID-19: A Review Study. Iran J Med Sci. 2021;46(1):1-14. doi: 10.30476/ijms.2020.87233.1730
- Ahmed S, Zimba O, Gasparyan A. Thrombosis in Coronavirus disease 2019 (COVID-19) through the prism of Virchow's triad. Clin Rheumatol. 2020;39(9):2529-43. doi: 10.1007/s10067-020-05275-1
- Kashi M, Jacquin A, Dakhil B. Severe arterial thrombosis associated with Covid-19 infection. Thromb Res. 2020;192:75-7. doi: 10.1016/j.thromres.2020.05.025
- Maiuolo J, Mollace R, Gliozzi M. The Contribution of Endothelial Dysfunction in Systemic Injury Subsequent to SARS-CoV-2 Infection. Int J Mol Sci. 2020;21(23):9309. doi: 10.3390/ijms21239309
- Colling M, Kanthi Y. COVID-19-associated coagulopathy: An exploration of mechanisms. Vasc Med. 2020;25(5):471-8. doi: 10.1177/1358863X20932640
- Zhang Y, Xiao M, Zhang S. Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19. N Engl J Med. 2020;382(17):e38. doi: 10.1056/NEJMc2007575
- Lax S, Skok K, Zechner P. Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome: Results from a Prospective, Single-Center, Clinicopathologic Case Series. Ann Intern Med. 2020;173(5):350-61. doi: 10.7326/M20-2566
- Nopp S, Moik F, Jilma B, et al. Risk of venous thromboembolism in patients with COVID-19: A systematic review and meta-analysis. Res Pract Thromb Haemost. 2020;4(7):1178-91. doi: 10.1002/rth2.12439
- Wichmann D, Sperhake J, Lütgehetmann M. Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study. Ann Intern Med. 2020;173(4):268-77. doi: 10.7326/M20-2003
- Iwasaki M, Saito J, Zhao H, et al. Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications. Inflammation. 2021;44(1):13-34. doi: 10.1007/s10753-020-01337-3
- Huertas A, Montani D, Savale L. Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)? Eur Respir J. 2020;56(1):2001634. doi: 10.1183/13993003.01634-2020
- Sollini M, Ciccarelli M, Cecconi M. Vasculitis changes in COVID-19 survivors with persistent symptoms: an [18F]-FDG-PET/CT study. Eur J Nucl Med Mol Imaging. 2020;1-7. doi: 10.1007/s00259-020-05084-3
- Fulchand S. Covid-19 and cardiovascular disease. BMJ. 2020;369:m1997. doi: 10.1136/bmj.m1997
- Shah P, Welt F, Mahmud E. Triage Considerations for Patients Referred for Structural Heart Disease Intervention During the COVID-19 Pandemic: An ACC/SCAI Position Statement. JACC Cardiovasc Interv. 2020;13(12):1484-8. doi: 10.1016/j.jcin.2020.04.001
- Авдеев С.Н., Адамян Л.В., Алексеева Е.И., и др. Профилактика, диагностика и лечение новой коронавирусной инфекции (2019-nCoV): Временные методические рекомендации. М., 2020. Версия 8.2020 [Avdeev SN, Adamian LV, Alekseeva EI, et al. Profilaktika, diagnostika i lecheniie novoi koronavirusnoi infektsii (2019-nCoV): Vremennyie metodicheskiie rekomendatsii. Moscow, 2020. Versiia 8.2020 (in Russian)].
- Thachil J, Tang N, Gando S. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. J Thromb Haemost. 2020;18(5):1023-6. doi: 10.1111/jth.14810
- Topal G, Loesch A, Dashwood M. COVID-19 – Endothelial Axis and Coronary Artery Bypass Graft Patency: A Target for Therapeutic Intervention? Braz J Cardiovasc Surg. 2020;35(5):757-63. doi: 10.21470/1678-9741-2020-0303
- Lei S, Jiang F, Su W. Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection. EClinicalMedicine. 2020;21:100331. doi: 10.1016/j.eclinm.2020.100331
- Jin Y, Ji W, Yang H, et al. Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches. Signal Transduct Target Ther. 2020;5(1):293. doi: 10.1038/s41392-020-00454-7
- Liu Z, Li J, Chen D. Dynamic Interleukin-6 Level Changes as a Prognostic Indicator in Patients With COVID-19. Front Pharmacol. 2020;11:1093. doi: 10.3389/fphar.2020.01093
- Gando S, Fujishima S, Saitoh D. The significance of disseminated intravascular coagulation on multiple organ dysfunction during the early stage of acute respiratory distress syndrome. Thromb Res. 2020;191:15-21. doi: 10.1016/j.thromres.2020.03.023
- Li J, Liu Z, Wu G. D-Dimer as a Prognostic Indicator in Critically Ill Patients Hospitalized With COVID-19 in Leishenshan Hospital, Wuhan, China. Front Pharmacol. 2020;11:600592. doi: 10.3389/fphar.2020.600592
- Biswas S, Thakur V, Kaur P, et al. Blood clots in COVID-19 patients: Simplifying the curious mystery. Med Hypotheses. 2021;146:110371. doi: 10.1016/j.mehy.2020.110371
- Chen J, Wang X, Zhang S. Characteristics of Acute Pulmonary Embolism in Patients With COVID-19 Associated Pneumonia From the City of Wuhan. Clin Appl Thromb Hemost. 2020;26:1076029620936772. doi: 10.1177/1076029620936772
- Tang N, Bai H, Chen X, et al. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020;18(5):1094-9. doi: 10.1111/jth.14817
- Hayıroğlu M, Çınar T, Tekkeşin A. Fibrinogen and D-dimer variances and anticoagulation recommendations in Covid-19: current literature review. Rev Assoc Med Bras. 2020;66(6):842-8. doi: 10.1590/1806-9282.66.6.842
- Zhou F, Yu T, Du R. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-62. doi: 10.1016/S0140-6736(20)30566-3
- Ingraham N, Barakat A, Reilkoff R. Understanding the renin-angiotensin-aldosterone-SARS-CoV axis: a comprehensive review. Eur Respir J. 2020;56(1):2000912. doi: 10.1183/13993003.00912-2020
- Varga Z, Flammer A, Steiger P. Endothelial cell infection and endotheliitis in COVID-19. Lancet. 2020;395(10234):1417-8. doi: 10.1016/S0140-6736(20)30937-5