Endocrine side effects during cancer treatment. Lecture for practitioners

Cover Page

Cite item

Full Text

Abstract

Targeted therapy and immune checkpoint inhibitors (ICI) are increasingly being used to treat many solid tumors. The use alpelisib and ICPI has a risk of side-effects, particularly endocrine dysfunctions. In this lecture, there are clearly stated: initial screening, monitoring, selection of therapy and emergency situations for each endocrinopathy, i.e. hyperglycemia during treatment with alpelisib and destructive thyroiditis and hypophysitis during treatment of ICI.

About the authors

Anastasiya A. Glibka

Endocrinology Research Centre

Email: troshina@inbox.ru
ORCID iD: 0000-0002-7324-8344

Graduate Student

Russian Federation, Moscow

Natalya V. Mazurina

Endocrinology Research Centre

Email: natalyamazurina@mail.ru
ORCID iD: 0000-0001-8077-9381
SPIN-code: 9067-3062

Cand. Sci. (Med.)

Russian Federation, Moscow

Ekaterina A. Troshina

Endocrinology Research Centre

Author for correspondence.
Email: troshina@inbox.ru
ORCID iD: 0000-0002-8520-8702

D. Sci. (Med.), Prof., Acad. RAS

Russian Federation, Moscow

References

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Figure 1. Risk stratification before starting alpelisib therapy (performed by the attending oncologist).

Download (229KB)
3. Figure 2. Mechanism of action of ICTIO [14, 15].

Download (370KB)

Copyright (c) 2022 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies