Visceral sensitivity index of patients with irritable bowel syndrome after COVID-19 infection

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Abstract

Aim. To perform comparative analysis of visceral sensitivity index (VSI) of patients with previously diagnosed irritable bowel syndrome (IBS) and of patients with IBS symptoms after COVID-19 infection.

Materials and methods. The study was carried out on the basis of University Clinical Hospital №1; 200 patients with COVID-19 infection were examined. Selection criteria were the recommendations of the Rome Consensus IV (2016). Fourteen patients met the criteria for IBS (Rome IV). Forty patients with a verified diagnosis of IBS before the COVID-19 pandemic (Group 2) were selected as a comparison group. The control group included 50 healthy respondents (group 3). Group 1 included 14 patients; Group 2 included 40 patients (54 patients in total): 37 women and 17 men. The control group included 50 patients: 23 men and 27 women. VSI was estimated in the studied groups.

Results. No statistically significant difference of VSI index (p>0.05) was revealed while comparing two studied groups (group 1 and group 2). In group 1 and group 2 the mean values of VSI were 24.57±5.47 and 33.98±2.55 respectively. Absence of significant differences allows to assume from the position of biopsychosocial model that the patients were initially predisposed to IBS development.

Conclusion. A new coronavirus infection is one of the triggers for the development of IBS 6 months after COVID-19 infection.

About the authors

Iana Yu. Feklina

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: janafeklina@gmail.com
ORCID iD: 0000-0003-2344-1629

Graduate Student, Sechenov First Moscow State Medical University (Sechenov University)

Russian Federation, Moscow

Marina G. Mnatsakanyan

Sechenov First Moscow State Medical University (Sechenov University)

Email: mnatsakanyan08@mail.ru
ORCID iD: 0000-0001-9337-7453

D. Sci. (Med.), Sechenov First Moscow State Medical University (Sechenov University)

Russian Federation, Moscow

Alexander P. Pogromov

Sechenov First Moscow State Medical University (Sechenov University)

Email: pogromov.alexander@yandex.ru
ORCID iD: 0000-0002-7426-4055

D. Sci. (Med.), Prof., Sechenov First Moscow State Medical University (Sechenov University)

Russian Federation, Moscow

Olga V. Tashchyаn

Sechenov First Moscow State Medical University (Sechenov University)

Email: olgatash1@rambler.ru
ORCID iD: 0000-0001-6759-6820

Cand. Sci. (Med.), Sechenov First Moscow State Medical University (Sechenov University)

Russian Federation, Moscow

References

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Supplementary files

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2. Fig. 1. Comparison of mean VSI values in group 1 and group 2.

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3. Fig. 2. Comparison of mean VSI values in men and women.

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4. Fig. 3. Mean values of VSI in groups 1 and 2 depending on IBS variant.

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