From eating to obesity: issues of diagnosis and neuroendocrine regulation. A review

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Abstract

The problem of eating disorders, as well as the problem of obesity, is multidisciplinary and does not lose its relevance. The violation of the food pattern is caused by the influence of many factors, such as genetic, humoral, psychological, psychosocial, etc. The implementation of eating behavior is carried out through neurohumoral interaction at various levels of regulation, including the structures of the central, autonomic nervous system and the gastrointestinal tract, the functional characteristics of which are currently time continue to be actively studied. The functional characteristics of the intestinal microbiota play a significant role in the hedonistic and humoral regulation of eating behavior. Alimentary obesity is considered as a psychosomatic disease, which is formed as a result of eating disorders by the type of overeating.

About the authors

Oksana V. Maksim

Kirov Military Medical Academy

Author for correspondence.
Email: ovmaks1611@mail.ru

endocrinologist

Russian Federation, Saint Petersburg

Vladimir V. Salukhov

Kirov Military Medical Academy

Email: ovmaks1611@mail.ru
ORCID iD: 0000-0003-1851-0941

D. Sci. (Med.), Prof.

Russian Federation, Saint Petersburg

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2. Figure 1. Energy homeostasis resulting from the integration of peripheral metabolic and CNS signals.

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3. Figure 2. GHS-R1a - secretagogue growth hormone receptors.

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