Email this article Biocompatibility of Biodegradable Polymer Films Based on Poly(lactic-co-glycolic acid) of Various Molecular Weights
- Authors: Baikin A.S.1, Sevost’yanov M.A.1, Nasakina E.O.1, Sergienko K.V.1, Kaplan M.A.1, Konushkin S.V.1, Kolmakova A.A.1, Yakubov A.D.1, Bunkin N.F.2,3, Gudkov S.V.3,4,5, Shatova L.A.6, Barinov S.M.1, Kolmakov A.G.1
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Affiliations:
- Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
- Bauman Moscow State Technical University
- Prokhorov General Physics Institute
- Lobachevsky State University of Nizhny Novgorod—National Research University
- Moscow Regional Research Clinical Institute
- Voronezh State Technical University
- Issue: Vol 10, No 4 (2019)
- Pages: 887-891
- Section: Article
- URL: https://journals.rcsi.science/2075-1133/article/view/208000
- DOI: https://doi.org/10.1134/S207511331904004X
- ID: 208000
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Abstract
Various poly(lactic-co-glycolic acid)-based polymeric films with various molecular weights were obtained. The mechanical characteristics of these films were investigated. It was shown that the obtained polymer films do not have a short-term toxic effect on mammalian cells. The percentage of actively dividing cells on such polymer films is 1.5–3.0 times higher than when grown on culture glass, and, accordingly, the cell layer is formed faster. The obtained poly(lactic-co-glycolic acid)-based polymer films are biocompatible.
About the authors
A. S. Baikin
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Author for correspondence.
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
M. A. Sevost’yanov
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
E. O. Nasakina
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
K. V. Sergienko
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
M. A. Kaplan
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
S. V. Konushkin
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
A. A. Kolmakova
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
A. D. Yakubov
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
N. F. Bunkin
Bauman Moscow State Technical University; Prokhorov General Physics Institute
Email: baikinas@mail.ru
Russian Federation, Moscow, 105005; Moscow, 117942
S. V. Gudkov
Prokhorov General Physics Institute; Lobachevsky State University of Nizhny Novgorod—National Research University; Moscow Regional Research Clinical Institute
Email: baikinas@mail.ru
Russian Federation, Moscow, 117942; Nizhny Novgorod, 603950; Moscow, 129110
L. A. Shatova
Voronezh State Technical University
Email: baikinas@mail.ru
Russian Federation, Voronezh, 394026
S. M. Barinov
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
A. G. Kolmakov
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences
Email: baikinas@mail.ru
Russian Federation, Moscow, 119334
