Brushite cement based on β-TCP for orthopedics

Abstract

The phase composition of brushite cement that is based on β-tricalcium phosphate (β-TCP) and monocalcium phosphate monohydrate (MCPM) is optimized. It is shown that an increase in the β-TCP/MCPM ratio from 1.0 to 1.35 leads to a 20% increase in the cement compressive strength. We assume that this is due to reinforcement of the cement with ceramic particles of β-TCP. Carbonated hydroxyapatite (CHA) granules that are introduced into the cement composition in the amount of 10 wt % also lead to a 20% increase in the cement compressive strength. The cement that is investigated is promising for use in osteoplastic surgery for healing of bone tissue defects that result from trauma and extensive surgery.