Experience with the use of a preparation containing polyhexanide and betaine in the treatment of secondary infected dermatoses

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Abstract

This article examines the problem of secondary infection in atopic dermatitis (AD), caused by impaired skin barrier function and dysbiosis, with a predominance of Staphylococcus aureus. The role of bacterial, fungal, and viral infections in aggravating the disease is emphasized. Three clinical cases demonstrate the effectiveness of a gel containing polyhexanide and betaine. Application of the gel ensured gentle cleansing of crusts and biofilm, exerted an antimicrobial effect, and created optimal conditions for regeneration, significantly increasing the effectiveness of subsequent anti-inflammatory therapy and achieving rapid relief of infection symptoms.

About the authors

Larisa S. Kruglova

Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation

Author for correspondence.
Email: kruglovals@mail.ru
ORCID iD: 0000-0002-5044-5265

Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology, Rector

Russian Federation, Moscow

Natalya V. Gryazeva

Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation

Email: tynrik@yandex.ru
ORCID iD: 0000-0003-3437-5233

Dr. Sci. (Med.), Professor, Department of Dermatovenereology and Cosmetology

Russian Federation, Moscow

Anait V. Tamrazova

Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation

Email: anaittamrazova@gmail.com
ORCID iD: 0000-0002-4672-697X

Cand. Sci. (Med.), Associate Professor, Department of Dermatovenereology and Cosmetology

Russian Federation, Moscow

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