🔧На сайте запланированы технические работы
25.12.2025 в промежутке с 18:00 до 21:00 по Московскому времени (GMT+3) на сайте будут проводиться плановые технические работы. Возможны перебои с доступом к сайту. Приносим извинения за временные неудобства. Благодарим за понимание!
🔧Site maintenance is scheduled.
Scheduled maintenance will be performed on the site from 6:00 PM to 9:00 PM Moscow time (GMT+3) on December 25, 2025. Site access may be interrupted. We apologize for the inconvenience. Thank you for your understanding!

 

Numerical simulation of the effect of localization of the front of cellular necrosis during cutaneous cryosurgery


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

In this paper, we consider the problem of planning and optimizing the destruction of the tumor tissue during cutaneous cryosurgery. A method of mounting additional heating elements is proposed as an approach to control propagation of the front of cellular necrosis. Mathematical simulation and Pareto optimality of calculable functions are used to improve the effectiveness of the proposed method. An explicit scheme that is based on the finite volume approximation of the Pennes bioheat transfer model is applied, together with an enthalpy method for computing blurred phase transitions. A flux relaxation method is used to improve the stability of the scheme.

About the authors

N. A. Kudryashov

Department of Applied Mathematics, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)

Author for correspondence.
Email: nakudr@gmail.com
Russian Federation, Moscow, 115409

K. E. Shilnikov

Department of Applied Mathematics, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)

Email: nakudr@gmail.com
Russian Federation, Moscow, 115409

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2016 Pleiades Publishing, Ltd.