Postoperative prolonged epidural analgesia using disposable elastomeric pumps in elderly patients after spinal neurosurgery
- Authors: Solenkova A.V.1, Lubnin A.Y.1, Ivanova O.N.1, Konovalov N.A.1, Korolishin V.A.1, Brinyuk E.S.1
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Affiliations:
- National Medical Research Center of Neurosurgery named N.N. Burdenko, Ministry of Health of the Russian Federation
- Issue: Vol 15, No 2 (2021)
- Pages: 137-146
- Section: Original articles
- URL: https://journals.rcsi.science/1993-6508/article/view/90105
- DOI: https://doi.org/10.17816/1993-6508-2021-15-2-137-146
- ID: 90105
Cite item
Abstract
BACKGROUND: Postoperative pain is a significant problem in patients that causes various complications.
AIM: To evaluate the efficacy and safety of prolonged epidural analgesia using
disposable elastomeric pumps in elderly patients undergoing spinal neurosurgery and its comparison with the traditional method of postoperative analgesia in 80 patients.
MATERIALS AND METHODS: Hemodynamic parameters were recorded and the efficiency of pain relief and nature of postoperative complications were assessed in comparable groups. The concentration of interleukin-6 (IL-6) and IL-2 were determined.
RESULTS: In the group with prolonged epidural analgesia with 0.2% ropivacaine solution, an adequate level of analgesia was achieved in 92% of the patients. The revealed changes in the blood serum levels of cytokines IL-6 and IL-2 may indicate a balanced response of the immune system in the group with prolonged epidural analgesia.
CONCLUSIONS: Prolonged epidural analgesia using disposable elastomeric pumps provides complete pain relief for patients and correction of individual links of the surgical stress response.
Full Text
##article.viewOnOriginalSite##About the authors
Alla V. Solenkova
National Medical Research Center of Neurosurgery named N.N. Burdenko, Ministry of Health of the Russian Federation
Author for correspondence.
Email: asolenkova@mail.ru
ORCID iD: 0000-0001-7081-2950
SPIN-code: 3274-6730
MD, PhD, DSc
Russian Federation, 16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047Andrey Yu. Lubnin
National Medical Research Center of Neurosurgery named N.N. Burdenko, Ministry of Health of the Russian Federation
Email: lubnin@nsi.ru
ORCID iD: 0000-0003-2595-5877
DMSc, MD, PhD, DSc, professor
Russian Federation, 16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047Olga N. Ivanova
National Medical Research Center of Neurosurgery named N.N. Burdenko, Ministry of Health of the Russian Federation
Email: oivanova@nsi.ru
ORCID iD: 0000-0003-1253-8337
Russian Federation, 16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
Nikolay A. Konovalov
National Medical Research Center of Neurosurgery named N.N. Burdenko, Ministry of Health of the Russian Federation
Email: NKonovalov@nsi.ru
ORCID iD: 0000-0002-9976-948X
SPIN-code: 9436-3719
MD, PhD, DSc
Russian Federation, 16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047Vasiliy A. Korolishin
National Medical Research Center of Neurosurgery named N.N. Burdenko, Ministry of Health of the Russian Federation
Email: vkorolishin@mail.ru
ORCID iD: 0000-0002-1727-5102
SPIN-code: 2798-1078
MD, PhD
Russian Federation, 16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047Evgeniy S. Brinyuk
National Medical Research Center of Neurosurgery named N.N. Burdenko, Ministry of Health of the Russian Federation
Email: brinya88@mail.ru
ORCID iD: 0000-0001-6184-7481
SPIN-code: 3381-3193
Russian Federation, 16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
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