The blockade of the sciatic nerve of a pharmaceutical composition of lidocaine and ropivacaine (2:1) with a short block of peripheral nerve and prolonged postoperative analgesia

The goal of this study is to optimize the intra- and postoperative analgesia by a pharmaceutical composition of ropivacaine and lidocaine in a ratio of 2:1, which has shorter time of sciatic nerve blockade and prolonged analgesic effect. Materials and methods. Achieved 40 blockades of the sciatic nerve under ultrasound guidance with the use of electrical stimulation of peripheral nerves. In the study, patients with the upcoming surgery in the knee joint were included, shin, ankle and foot. In the first group of the sciatic nerve blockade was performed with 5 ml 0.75% naropina combined with 5 ml 1% lidocaine; in the second group used a combination of 1% lidocaine and 0.75% ropivacaine (2:1) in a volume of 10 ml. In addition, the femoral nerve blockade was performed. Evaluation time of sensory, motor blocks and duration of analgesia were performed since the beginning of the administration of local anesthetic solution into the fascial sheath of the sciatic nerve. Results. In all cases the pain relief was effective. Time of onset of complete sensory block in the 1st and 2nd groups was 13 (12.5; 14) and 14 minutes (13; 15.5) min (p> 0.05), respectively. Time of onset of complete motor block was 14 (12; 17.5) minutes; Group 2 - 16 (14; 17.5) min (p> 0.05). The duration of postoperative analgesia in group 1 was 8 (7, 8), in group 2 - 7.5 (6.75; 8) hours (p> 0.05). Conclusion. Use of a pharmaceutical composition of ropivacaine and lidocaine in a ratio of 2:1 in a volume of 10 ml for sciatic nerve blockade causes complete nerve blockade by 16 (14; 17.5) minutes without sacrificing analgesia.

mixture of local anesthetics, lidocaine, ropivacaine, sciatic nerve, ultrasonic control