INFLUENCE OF THE ANESTHESIA METHOD ON THE OUTCOMES OF CARDIAC SURGERY OF DIFFERENT COMPLEXITY IN CHILDREN


Cite item

Full Text

Abstract

The Aristotle score: a complexity-adjusted method to evaluate surgical results. For an assessment of dynamics of quality of the provided cardio-surgical help, comparison of a perioperative case rate and a mortality depending on the degree of surgical risk at cardiac interventions the Aristotle score is used. Thoracic epidural anesthesia (TEA) in comparison with high-opioids intravenous anesthesia (IVA) contributes to hemodynamics stability and early activation of patients. Objective: To analyze a current of the perioperative period at cardiac interventions in children with various categories of complexity of surgical intervention on «Aristotle score» depending on a type of anesthesia. Materials and methods. The 139 children with congenital heart diseases (CHD) underwent surgical correction. Patients were treated in Federal State Budgetary Institution of the Russian Ministry of Health (Penza), and «Almazov National medical research Centre» from 2008 to 2017 yrs. Patients (139 people, the mean age M (SD) of 7.6 (5.6) months of life) were divided into groups according to the categories of operational complexity presented in the Aristotle score. The group 1 consisted of 85 (61.2%) patients underwent interventions of second category of complexity, the group 2 consisted of 49 (39.8%) patients underwent interventions of 3 and 4 categories of complexity. Results. In cardiosurgical operations of the 2nd category of the Aristotle scale complexity a significant positive effect of TEA on the perioperative period was revealed in the form of a decrease in the severity of intraoperative heart failure and the level of glycaemia, the total number of postoperative complications and the time of patients’ staying on mechanical ventilation, as well as the duration of ICU stay and the decrease thrombocytopenia severity and frequency. In operations of grade 3 and 4, in which the duration of extracorporeal circulation was greater, the use of TEA did not have a significant positive effect on the incidence of postoperative complications, but after epidural anesthesia the mean duration of the patients’ stay on the mechanical ventilation and in the ICU was also significantly less. Apparently, the result is a consequence of a lesser severity of heart failure and early activation of patients by excluding the use of opioids, which have a depressing effect on the central nervous system, cardiac, respiratory and other systems. It can also be assumed that the administration of local anesthetics within 24 hours after the operation maintained sympatholytic and antiarrhythmic effects, and also prevented the complications development as a result of effective analgesia. Sufficiently convincing evidence of high antinociceptive activity of TEA is the possibility of safe extubation of patients in both the 2-d and 3-d categories of surgical complexity demonstrated in our study already in the operating room. Conclusion. Use of high TEA as a component of the combined anesthesia at surgical correction of CHD in young children has positive impact on a current of the perioperative period in the form of decrease in severity of heart and respiratory failure, duration of respiratory support, early activation and reduction of ICU stay.

About the authors

Lyaylya Z. Biktasheva

Almazov National Medical Research Centre

Email: biktash10@mail.ru
the anesthesiologist , office of anesthesiology-resuscitation with chambers of resuscitation and intensive therapy No. 11 for children. Almazov National Medical Research Centre of the Russian Ministry of Health. 197341, St. Petersburg, Russia 197341, St. Petersburg, Russia

I. N Menshugin

Almazov National Medical Research Centre

197341, St. Petersburg, Russia

V. A Mazurok

Almazov National Medical Research Centre

197341, St. Petersburg, Russia

A. E Bautin

Almazov National Medical Research Centre

197341, St. Petersburg, Russia

References

  1. Cory M. Alwardt, Daniel Redford, Douglas F. Larson. General Anesthesia in Cardiac Surgery: A Review of Drugs and Practices. J. Extra Corpor. Technol. 2005; 37 (2): 227-35.
  2. Tenling A, Joachimsson PO, Tyden H, Hedenstierna G. Thoracic epidural analgesia as an adjunct to general anaesthesia for cardiac surgery. Effects on pulmonary mechanics. Acta Anaesthesiol. Scand. 2000; 44: 1071-6.
  3. R Kowalewski, D Seal, T Tang, C Prusinkiewicz, D Ha. Neuraxial anesthesia for cardiac surgery: thoracic epidural and high spinal anesthesia - why is it different? HSR Proc. Intensive Care Cardiovasc. Anesth. 2011; 3 (1): 25-28.
  4. Stefano Casalino, MD, Fabio Mangia, MD, Edmond Stelian, MD, Eugenio Novelli, PhD, Marco Diena, MD, and Ugo F. Tesler, High Thoracic Epidural Anesthesia in Cardiac Surgery. Risk Factors for Arterial Hypotension. Tex. Heart Inst. J. 2006; 33 (2): 148-53.
  5. Scott NB, Turfrey DJ, Ray DA, Nzewi O, Sutcliffe NP, Lal AB, et al. A prospective randomized study of the potential benefits of thoracic epidural anesthesia and analgesia in patients undergoing coronary artery bypass grafting. Anesth. Analg. 2001; 93: 528-35.
  6. Steven, James M., McGowan, Francis X. Jr. Neuraxial Blockade for Pediatric Cardiac Surgery: Lessons Yet to Be Learned. Anesthesia & Analgesia: 2000; 90 (5): 1011-3.
  7. Gail K. Wong, Abeer A. Arab, Sue C. Chew, Basem Naser, Mark W. Crawford. Reports of original investigations. Major complications related to epidural analgesia in children: a 15-year audit of 3,152. Can. J. Anaesth. 2013; 60 (4): 355-63.
  8. Бикташева Л.З., Меньшугин И.Н., Мазурок В.А., Баутин А.Е., Карчевская К.В. Торакальная эпидуральная анестезия у детей раннего возраста при хирургической коррекции врожденных пороков сердца. Анестезиология и реаниматология. 2017; 62 (2): 117-23
  9. F. Lacour-Gayet, D. Clarke, J. Jacobs, J. Comas, S. Daebritz, W. Daenen, W. Gaynor, L. Hamilton, M. Jacobs, B. Maruszsewski, M. Pozzi, T. Spray, G. Stellin, C. Tchervenkov, C. Mavroudis and The Aristotle Invited paper. The Aristotle score: a complexity-adjusted method to evaluate surgical results. Committee European Journal of Cardio-thoracic Surgery 2004 (25): 911-924.
  10. Stark J, Gallivan S, Lovegrove J, Hamilton JRL, Monro JL, Pollock JCS, Watterson KG. Mortality rates after surgery for congenital heart defects in children and surgeon’s performance. Lancet. 2000; 355: 1004-7.
  11. К.Э. Диасамидзе, Ю.А. Кольцов, Д.Я. Хинчагов, К.В. Мумладзе, М.М. Рыбка. Результаты применения высокой грудной эпидуральной анестезии у больных с дефектом межпредсердной перегородки. Бюллетень НЦССХ им. А.Н. Бакулева РАМН, 2014; 15(5).
  12. Carmona F., Mata K.M., Oliveira M.S. et al. Cardiology and Cardiovascular Medicine book. ISBN 978-953-51-0993-8, Published: February 15, 2013 under CC BY 3.0 license. © The Author(s). Chapter 2 Myocardial Ischemia in Congenital Heart Disease: A Review.
  13. Knowles R.L., Bull C., Wren C., Wade A., Goldstein H., Dezateux C. Modelling Survival and Mortality Risk to 15 Years of Age for a National Cohort of Children with Serious Congenital Heart Defects Diagnosed in Infancy UK Collaborative Study of Congenital Heart Defects) collaborators http://dx.doi.org/10.1371/journal.pone.0106806 Published: September 10, 2014.
  14. Gaies M.G., Jeffries H.E., Niebler R.A., Pasquali S.K. Vasoactive-Inotropic Score (VIS) is Associated with Outcome After Infant Cardiac Surgery: An Analysis from the Pediatric Cardiac Critical Care Consortium (PC) and Virtual PICU System Registries. Pediatr. Crit. Care Med. 2014; 15 (6): 529-537.
  15. Овечкин А.М., Осипов С.А. Антикоагулянты и нейроаксиальная анестезия (аналитический обзор). Вестник интенсивной терапии. 2006; ( 3): 15-21.
  16. Andreas Greinacher, Kathleen Selleng. Thrombocytopenia in the Intensive Care Unit Patient. Hematology. ASH Education Book. 2010; 2010 (1): 135-143.

Copyright (c) 2017 Eco-Vector


 


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies