INTRAVENOUS LIDOCAINE INFUSION AS A PERSPECTIVE COMPONENT OF MULTIMODAL ANALGESIA, WHICH AFFECTS ON EARLY POSTOPERATIVE OUTCOME


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Abstract

The review represents the analysis of literature data on the effectiveness of intravenous lidocaine infusion as a component of multimodal analgesia. The data suggests that intraoperative lidocaine infusion at the rate of 1-1.5 mg /kg /h (if it’s possible - with the prolongation to the early postoperative period) is an advisable component of the multimodal analgesia. This technique can reduce the intraoperative doses of propofol, MAC of inhalation anesthetics, also reduces the postoperative need for analgesics and the frequency of postoperative nausea and vomiting. Furthermore, lidocaine infusion permits to shorten the time of resolution of postoperative ileus (approaching in this the effect of epidural analgesia) and, perhaps, to reduce the frequency and severity of postoperative cognitive dysfunction. The most effective use of this technique is in laparoscopic surgery on the abdominal and pelvic organs.

About the authors

Alexei M. Ovechkin

I.M. Sechenov First Moscow State Medical University

Email: ovechkin_alexei@mail.ru
MD, PhD, DSc, professor of the Department of anesthesiology and resuscitation, I.M. Sechenov First Moscow State Medical University, Moscow, 119991, Russian Federation 119991, Moscow, Russian Federation

A. A Becker

I.M. Sechenov First Moscow State Medical University

119991, Moscow, Russian Federation

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