Efficacy of ultrasound-assisted pterygopalatine block using a posterior-to-anterior subzygomatic approach in eye enucleation: a prospective randomized comparative study

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

Background: Pterygopalatine block (PPB) is widely indicated in ophthalmology due to its simultaneous impact on sympathetic, parasympathetic, and nociceptive innervation. Ultrasound (US) guidance enhances block accuracy; however, clinical data on the efficacy of US-assisted PPB using different approaches remain limited.

Aim: To compare the efficacy of US-guided PPB using posterior-to-anterior subzygomatic and suprazygomatic approaches in patients undergoing eye enucleation.

Materials and methods: A prospective randomized study was conducted. For postoperative analgesia, PPB was performed in Group 1 (n=30) using the posterior-to-anterior subzygomatic approach and in Group 2 (n=30) using the suprazygomatic approach. The time required to perform the block, onset of analgesia, changes in arterial blood pressure (BP) and heart rate (HR), and technical aspects of block execution were evaluated.

Results: The interval between block administration and the onset of analgesia was significantly shorter in Group 1 (5.3±1.0 minutes) compared to Group 2 (10.1±1.4 minutes, p=0.041). Significant differences were also observed in the time to decreased skin sensitivity in the infraorbital area and time to pain relief: 8.9±0.9 and 13.5±0.7 minutes in Group 1 versus 14.4±1.2 and 19.6±1.7 minutes in Group 2 (p=0.037 and p=0.034, respectively). Mean arterial pressure and HR were lower in Group 1 (91.2±6.5 mmHg and 88.5±5.2 bpm) compared to Group 2 (101.1±6.6 mmHg and 105.3 ± 8.4 bpm, p=0.001). During the suprazygomatic PPB (Group 2), 53.3% (n=16) of patients reported discomfort, with a mean pain score of 2.3±0.5 on the numeric rating scale.

Conclusion: For managing pain after eye enucleation, ultrasound-assisted PPB using the posterior-to-anterior subzygomatic approach is the method of choice. Compared to the suprazygomatic approach, it provides faster onset of effective analgesia, greater patient comfort, and improved safety.

About the authors

Irina G. Oleshchenko

Fyodorov “Eye Microsurgery” Federal State Institution; Irkutsk State Medical University

Author for correspondence.
Email: iga.oleshenko@mail.ru
ORCID iD: 0000-0003-1642-5276
SPIN-code: 8824-1216

MD, Cand. Sci. (Medicine), anesthesiologist-resuscitator, Irkutsk Branch

Russian Federation, 337 Lermontov street, 664033 Irkutsk; Irkutsk

Dmitrii V. Zabolotskii

Saint-Petersburg State Pediatric Medical University; Turner National Medical Research Center for Pediatric Traumatology and Orthopedics

Email: zdv4330303@gmail.com
ORCID iD: 0000-0002-6127-0798
SPIN-code: 6726-2571

MD, Dr. Sci. (Medicine), Professor

Russian Federation, 2 Litovskaya street, 194100 Saint Petersburg; Pushkin

Aleksandr V. Mankov

Irkutsk State Medical University

Email: man-aleksandrv@yandex.ru
ORCID iD: 0000-0001-8701-6432
SPIN-code: 7135-2828

MD, Cand. Sci. (Medicine), anesthesiologist-resuscitator

Russian Federation, Irkutsk

Victor A. Koriachkin

Saint-Petersburg State Pediatric Medical University; Turner National Medical Research Center for Pediatric Traumatology and Orthopedics

Email: vakoryachkin@mail.ru
ORCID iD: 0000-0002-3400-8989
SPIN-code: 6101-0578

MD, Dr. Sci. (Medicine), Professor

Russian Federation, 2 Litovskaya street, 194100 Saint Petersburg; Pushkin

References

  1. Robbins MS, Robertson CE, Kaplan E, et al. The Sphenopalatine Ganglion: Anatomy, Pathophysiology, and Therapeutic Targeting in Headache. Headache. 2016;56(2):240–258. doi: 10.1111/head.12729
  2. Ho KWD, Przkora R, Kumar S. Sphenopalatine ganglion: block, radiofrequency ablation and neurostimulation — a systematic review. J Headache Pain. 2017;18(1):118. doi: 10.1186/s10194-017-0826-y
  3. Piagkou M, Demesticha T, Troupis T, et al. The pterygopalatine ganglion and its role in various pain syndromes: from anatomy to clinical practice. Pain Pract. 2012;12(5):399–412. doi: 10.1111/j.1533-2500.2011.00507.x
  4. Chiono J, Raux O, Bringuier S, et al. Bilateral suprazygomatic maxillary nerve block for cleft palate repair in children: a prospective, randomized, double-blind study versus placebo. Anesthesiology. 2014;120:1362–1369 doi: 10.1097/ALN.0000000000000171
  5. Marhofer P. Fundamentals of regional anesthesia with ultrasound navigation: Principles and practice. New York: Oxford University Press; 2014. 236 p.
  6. Allam AE, Khalil AAF, Eltawab BA, et al. Ultrasound-Guided Intervention for Treatment of Trigeminal Neuralgia: An Updated Review of Anatomy and Techniques. Pain Res Manag. 2018;2018:5480728. doi: 10.1155/2018/5480728
  7. Khonsary SA, Ma Q, Villablanca P, et al. Clinical functional anatomy of the pterygopalatine ganglion, cephalgia and related dysautonomias: A review. Surg Neurol Int. 2013;4(Suppl 6):422–428. doi: 10.4103/2152-7806.121628
  8. Iwanaga J, Wilson C, Simonds E, et al. Clinical Anatomy of Blockade of the Pterygopalatine Ganglion: Literature Review and Pictorial Tour Using Cadaveric Images. Kurume Med J. 2018;65(1):1–5. doi: 10.2739/kurumemedj.MS651001
  9. Dadure C, Motais F, Ricard C, et al. Continuous peripheral nerve blocks at home for treatment of recurrent complex regional pain syndrome I in children. Anesthesiology. 2005;102(2):387–391. doi: 10.1097/00000542-200502000-00022
  10. Zabolotskii DV, Koryachkin V.A., Ulrikh G.E. Postoperative analgesia in children. Are there any methods available today? Regional anesthesia and acute pain management. 2017;30(2):76–88. doi: 10.18821/1993-6508-2017-11-2-64-72
  11. Oleshchenko IG, Yurieva TN, Zabolotskii DV. The effectiveness of the use of therapeutic blockade for the purpose of anesthesia in adults: a systematic review and meta-analysis. Kuban Scientific Medical Bulletin. 2023;30(2):76–88. doi: 10.25207/1608-6228-2023-30-2-76-88
  12. Smith CR, Helander E, Chheda NN. Trigeminal nerve blockade in the pterygopalatine fossa for the management of postoperative pain in three adults undergoing tonsillectomy: A Proof-of-Concept report. Pain Med. 2020;21(10):2441–2446. doi: 10.1093/pm/pnaa062
  13. Mesnil M, Dadure C, Captier G, et al. A new approach for perioperative analgesia of cleft palate repair in infants: The bilateral suprazygomatic maxillary nerve block. Paediatr Anaesth. 2010;20(4):343–349. doi: 10.1111/j.1460-9592.2010.03262.x
  14. Zabolotskii DV, Malashenko NS, Mankov AV. Ultrasound navigation of invasive manipulations in anesthesiology. Siberian Medical Journal. 2012;113(6):15–20. EDN: PFFBQH
  15. Neuburger M, Büttner J. Complications of peripheral regional anesthesia. Anaesthesist. 2011;60(11):1014–1026. doi: 10.1007/s00101-011-1955-3
  16. Elhadi AM, Zaidi HA, Yagmurlu K, et al. Infraorbital nerve: a surgically relevant landmark for the pterygopalatine fossa, cavernous sinus, and anterolateral skull base in endoscopic transmaxillary approaches. J Neurosurg. 2016;125(6):1460–1468. doi: 10.3171/2015.9.JNS151099
  17. Rerkasem A, Orrapin S, Howard DP, et al. Local versus general anaesthesia for carotid endarterectomy. Cochrane Database Syst Rev. 2021;10(10):CD000126. doi: 10.1002/14651858.CD000126.pub5
  18. Zajcsev AYu, Svetlov VA, Dubrovin KV. Regional anesthesia of the trigeminal nerve in craniofacial surgery. Regional Anesthesia and Acute Pain Management. 2018;12(1):15–23. doi: 10.18821/1993-6508-2018-12-1-15-23
  19. Neal JM, Bernards CM, Hadzic A, et al. ASRA Practice Advisory on Neurologic Complications in Regional Anesthesia and Pain Medicine. Reg Anesth Pain Med. 2008;33(5):404–415. doi: 10.1016/j.rapm.2008.07.527

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. The location of the sensor and the position of the needle when performing the ultrasound-navugated PPB (original drawing). Blue rectangle — sensor position, 1 — posterior-anterior infrazygomatic approach, 2 — supra-zygomatic approach, A, Б — needle position change).

Download (224KB)

Copyright (c) 2024 Eco-Vector

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).